ophthalmoplegia

CNS tuberculoma can have varied clinical presentation ranging from mild headache, convulsions, hemiplegia, cranial nerve palsies and also rarely with panhypopituitarism (2), bilateral internuclear ophthalmoplegia (3), one and half syndrome (4) & eight and half syndrome.

The PEO1 (C10ORF2) mutations are associated with autosomal dominant progressive external ophthalmoplegia (PEO) (PEOA3), parkinsonism, as well as infantile-onset spinocerebellar ataxia.

She made a gradual improvement over the following days, making spontaneous respiratory efforts on day 10, with slow resolution of her ophthalmoplegia, and slow improvement in her motor function and autonomic dysfunction.

Clonal expansion of mitochondrial DNA with multiple deletions in autosomal dominant progressive external ophthalmoplegia.

The MFS is seen in two patients who had ataxia, areflexia, and ophthalmoplegia affecting 3, 4, and 6 cranial nerve.

The Tolosa-Hunt syndrome (THS) is characterized by painful ophthalmoplegia that is steroid responsive.

She was diagnosed with MS because of the radiological features of the lesions and had no relapse under glatiramer acetate therapy Her neurological examination a year later was within normal limits except for a mild left internuclear ophthalmoplegia that was a sequel of the initial attack and her EDSS was 2.

Neurological examination showed that total ophthalmoplegia with ptosis, mydriasis, decreased vision and loss of pupil reflex on the right side.

Bilateral internuclear ophthalmoplegia is almost always caused by a demyelinating disorder.

External signs include chemosis, external ophthalmoplegia, increased resistance to retropulsion, orbital ecchymosis, proptosis, and subconjunctival hemorrhage.

Strabismus and mitochondrial defects in chronic progressive external ophthalmoplegia.

Subsequently, the patient's condition declined over the next few days, and he expired after developing an acute ischemic infarction in the left basal ganglia with ophthalmoplegia and left cavernous sinus thrombosis.

31%) patients had vertigo or dizziness accompanied with symptoms of Horner's syndrome, limb ataxia, laryngeal and pharyngeal paralysis, dysphagia, dysarthria, visual disturbance, diplopia, gaze palsies, nystagmus, internuclear ophthalmoplegia, ataxia, drop attacks, face and extremity weakness, numbness, or reduced consciousness etc.

dilated pupils), external and internal ophthalmoplegia and paralysis of facial muscles and other muscles innervated by the cranial nerves, leading to dysarthria, dysphonia, and dysphagia.

Other, less frequent, clinical variants are the Miller Fisher syndrome10 of ophthalmoplegia, ataxia and areflexia, pharyngeal-cervical-brachial variant, paraparetic variant (mainly involving the lower limbs), pure Sensory GBS and acute pandysautonomia.