A 15-day study was performed to evaluate the repeated dose efficacy of the pomegranate peel extract and compare it with nystatin
in the 35 Wistar rats according to the standard protocols of the Transitional Guidance on the Biocidal Products Regulation.
On the other hand, chloramphenicol (for bacteria) and nystatin
(for fungi), which were used as positive controls, showed strong antimicrobial activities against the tested Gram-positive bacteria, Gram-negative bacteria, and fungi with inhibition zones ranging from 20 [+ or -] 0.5 to 25 [+ or -] 0.6.
albicans strains to nystatin
, we determined the MIC of nystatin
, using the microdilution technique in a sterile, 96-well, U-bottom plate (Kasvi, Italy), in the presence of a sub-MIC of citral (MIC/8) [31, 32].
For candida species, all were susceptible to amphotericin B, nystatin
, fluconazole, flucytosine, ketoconazole and econazole, while 3(60%) were resistant to miconazole.
Methods: It was an interventional, quasi experimental study in which tissue conditioner with Nystatin
(500,000 units) and without Nystatin
was applied on the fitting surface of upper denture.
It was noted from the study that overall, Candida species was sensitive to amphotericin-B in 95.4% cases, to voriconazole in 77.8%, to nystatin
in 69.4%, fluconazole in 64.1% and itraconazole in 63.9%.
Selected fungal isolates were tested against four antifungal drugs using readily available antifungal discs (Amphotericin-B, 100IU; Clotrimazole, 10mcg; Fluconazole, 10 mcg; Nystatin
100 IU) from Hi-Media Laboratories Ltd., Mumbai.
(Tystatin) Oral Suspension; Dexamethasone Sodium Phosphate + Neomycin Sulfate (Archidex) eyeear drops; Lansoprazole 30 mg delayedrelease capsule; Ketoconazole (Ninazol) 200 mg tablet; Paracetamol (SaRa) 500 mg tablet;
Topical azoles are more efficient than local nystatin
in treating uncomplicated VVC (18).
(5) Invitro studies on ketoconazole, Miconazole, nystatin
, Itraconazole combined with various tissue conditioners reported 100% efficacy in inhibiting C.
Recent treatment with hydrocortisone 1% cream and nystatin
cream (100,000 U/gm) for 1 week resulted in no improvement.
(NYS) or fungicidin (molar mass 926.13 g [mol.sup.-1]) is an antibiotic of the polyene group extracted from Streptomyces nursei microorganism cultures.
(10) He reported good responses, sometimes dramatic, to nystatin
and desensitization with Candida extract.
The ancient antifungal antibiotic nystatin
is a far cheaper alternative, but should be given at 100,000 units daily per vagina only.
Although it was patented back in 1957 as the world's first antifungal, antibiotic nystatin
upstaged newer antifungal agents when used to treat vulvovaginal candidiasis caused by Candida glabrata in sequential.