nucleoside


Also found in: Dictionary, Medical, Encyclopedia, Wikipedia.
Graphic Thesaurus  🔍
Display ON
Animation ON
Legend
Synonym
Antonym
Related
  • noun

Words related to nucleoside

a glycoside formed by partial hydrolysis of a nucleic acid

References in periodicals archive ?
Although most cells are capable of de novo nucleoside biosynthesis, the cellular nucleotide pool is preferentially maintained via the more energy efficient "salvage pathway" involving recycling and uptake of extracellular hydrophilic nucleosides by specialized integral membrane proteins, termed nucleoside transporters (NTs) (Molina-Arcas et al.
A novel nucleoside reverse transcriptase inhibitor candidate - EFdA (4'-ethynyl-2-fluoro-2'-deoxyadenosine) - has shown antiviral activity toward highly resistant HIV strains.
We discovered the structure of the transporter molecule, and now we believe it is possible to improve nucleoside drugs to be better recognized by a particular form of the transporter molecule that resides in certain types of tissue.
Neither Videx nor any other nucleoside had any impact on cardiovascular disease risk or on these heart disease markers.
TORONTO -- A large, randomized comparison of three standard regimens for the initial treatment of HIV has demonstrated that all three are safe and effective, but a regimen of efavirenz plus two nucleosides was significantly better at reducing HIV viral load, investigators reported at the 16th International AIDS Conference.
TORONTO -- A large, randomized comparison of three standard regimens for initial treatment of HIV has shown that all are safe and effective, but a regimen of efavirenz plus two nucleosides was significantly better at reducing HIV viral load, investigators said at the 16th International AIDS Conference.
Reverset is a nucleoside analog reverse transcriptase inhibitor that is being developed as a once-daily oral HIV therapy by Incyte Corporation and Pharmasset, Inc.
Also, TDM cannot be used for nucleosides because of their intracellular activity (blood plasma levels may not accurately be a reflection of drug penetration and therapeutic activity).
Approved June 24, 1996 for use in combination with nucleoside analogues for the treatment of HIV-infected adults experiencing clinical and/or immunologic deterioration.
Nucleoside Analogue Reverse Transcriptase Inhibitors Generic Name Initials Trade Name Manufacturer Didanosine (1990) ddl Videx Bristol-Myers Squibb Lamivudine (1995) 3TC Epivir Glaxo Wellcome Stavudine (1994) d4T Zerit Bristol-Myers Squibb Zalcitabine (1992) ddC HIVID Hoffmann-LaRoche Zidovudine (1987) AZT/ZDV Retrovir Glaxo Wellcome Table 2.
They bind to a cleft on the enzyme that normally locks onto a nucleoside, one of the building blocks of DNA.
Nasdaq: ISIS) with nucleoside phosphoramidites at quantities up to 100 kg.
Nucleoside triphosphates and their analogs; chemistry, biotechnology, and biological applications.
Clevudine is an oral, once-daily nucleoside analog drug candidate for the treatment of HBV that was shown to be well tolerated and potent in previously completed clinical studies.
Although the effect has been associated with both nucleoside analogue reverse transcriptase inhibitors (NRTI) and protease inhibitors, not all of the drugs in both classes are equal in this regard, prompting investigators to consider new combinations that might have more favorable effects on fat distribution.
Full browser ?