Presumptive treatment of sexual contacts reduces the risk for reinfection and is recommended for STI syndromes such as nongonococcal urethritis
Azithromycin treatment failure in Mycoplasma genitalium-positive patients with nongonococcal urethritis
is associated with induced macrolide resistance.
genitalium is associated with 15%-22% of nongonococcal urethritis
cases, and 10%-15% of cervicitis cases, and in many settings is more common that Neisseria gonorrhoeae with treatment outcomes often far worse," said Lisa E.
Minocycline was originally developed to treat a wide array of diseases such as susceptible bacterial infections of both Gram-negative and Gram-positive organisms and is currently recommended for the treatment of anthrax (inhalational, cutaneous, and gastrointestinal), moderate-to-severe acne, meningococcal (asymptomatic) carrier state, Rickettsial diseases (including Rocky Mountain spotted fever, Q fever), nongonococcal urethritis
, gonorrhoea, acute intestinal amoebiasis, respiratory tract infection, skin/soft tissue infections, and chlamydial infections (1-3).
Previous reports suggest that women who are sexual contacts of men with nongonococcal urethritis
rarely develop symptomatic oropharyngeal infection following fellatio.
Patient is a sexual gonorrhoeae contact of a person known to have gonorrhea, chlamydia, or nongonococcal urethritis
Acute Either of the following: An acute illness with hepatitis A * Alanine 1) discrete onset of aminotransferase symptoms and or aspartate aminotransferase greater 2) jaundice or elevated than two times the upper serum aminotransferase limit of normal levels and Positive IgM antibody * ICD-9 code 782.
Chlamydia trachomatis also can travel up the urethra in men infecting the epididymis, causing epididymitis and nongonococcal urethritis
(Uphold and Graham, 2003).
Genital infection with Chlamydia is the most common bacterial sexually transmitted disease in the United States and is responsible for about 40% of nongonococcal urethritis
Epidemiology of venereal urethritis: Comparison of gonorrhea and nongonococcal urethritis
The history of this research effort traces back to the discovery of a previously unknown microorganism in the genitourinary tract of two men suffering from nongonococcal urethritis
(NGU), which is diagnosed when examination findings or microscopy indicate inflammation without GNID is caused by C.
Mycoplasma genitalium is a sexually transmitted bacterium able to cause acute and chronic nongonococcal urethritis
(NGU) in men [1, 2] and urethritis, cervicitis, and pelvic inflammatory disease (PID) in women [1-3], although in many cases the infection is asymptomatic [4, 5].
In the 1980s a new species of Mycoplasma was isolated from the urogenital tract of men with nongonococcal urethritis
, Mycoplasma genitalium.
Mycoplasma genitalium is a sexually transmitted pathogen which was first discovered in 1980 in the urinary tracts of two men with symptomatic nongonococcal urethritis