nodes of Ranvier
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Related to nodes of Ranvier: myelin sheath, multiple sclerosis, Neurotransmitters, axon, action potential
- noun
Also found in: Dictionary, Medical, Encyclopedia, Wikipedia.
References in periodicals archive
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Myelinated fibers were identified by the presence of either NaD channel clusters at the nodes of Ranvier (data not shown) or MAG clusters at the paranodal regions.
2004) [beta]IV spectrins are essential for membrane stability and the molecular organization of nodes of Ranvier.
Hickman's team has now achieved the first successful model nodes of Ranvier formation on motor nerves in a defined serum-free culture system.
Researchers have long recognized the need for lab-grown motor nerve cells that myelinate and form nodes of Ranvier in order to use controlled lab conditions to zero in on the causes of demyelination.
The team then knocked out nsf in zebrafish, and showed that this protein is indeed required for the formation of the nodes of Ranvier and, ultimately, the myelination of nerve fibers.
We demonstrated that GFP-OECs form compact myelin and establish ultrastructurally intact nodes of Ranvier [62].
The accumulation of ion channels at nodes of Ranvier is an essential feature of rapid saltatory nerve conduction.
The nodes of Ranvier lie in the separations between the myelinated sections (Fig 1).
Such studies at NYU have demonstrated that at the interruptions in the myelin sheath called the nodes of Ranvier, the nerve fiber membrane has high concentrations of protein molecules corresponding to the sodium channels essential for the conduction of nerve impulses that jump from node to node.
similar to nodes of Ranvier in myelinated axons (9).
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