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Related to neuraminidase: sialic acid, Neuraminidase inhibitor
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  • noun

Synonyms for N

a common nonmetallic element that is normally a colorless odorless tasteless inert diatomic gas

the cardinal compass point that is at 0 or 360 degrees

a unit of force equal to the force that imparts an acceleration of 1 m/sec/sec to a mass of 1 kilogram


(of a solution) concentration expressed in gram equivalents of solute per liter

References in periodicals archive ?
The good news is that ways to boost IAP levels and inhibit neuraminidase activity exist.
Its product development pipeline also includes VaxArray reagent kits for pandemic hemagglutinin and flu neuraminidase.
Neuraminidase inhibitors for influenza B virus infection: efficacy and resistance.
Other reactions included a risk of neuropsychiatric events such as confusion or delirium, as well as serious skin reactions, although these are similar reactions to other neuraminidase inhibitors.
The frequency of H1N1 pdm09 viruses carrying neuraminidase [NA] H275Y remained low during both seasons; this mutation confers resistance to oseltamivir and peramivir," said Margaret Okomo-Adhiambo, Ph.
Director of the Office of Antimicrobial Products at the FDA, Edward Cox, said, "Rapivab is the third neuraminidase inhibitor approved by the FDA to treat flu infection, but the first approved as an intravenous formulation.
Oseltamivir, the neuraminidase inhibitor, and amantadine, an M2 ion channel inhibitor, face 90% and 100% resistance respectively, in some areas.
1]-transferrin was present in serum but absent in drainage fluid, additional neuraminidase activity was suspected.
Using a novel technique that presented viral particles with magnetic beads coated with different forms of mucin (the glycoproteins that comprise mucus) and varying known amounts of sialic acids, Gagneux and colleagues demonstrated that flu viruses counteract the natural barrier by also using neuraminidase to cut themselves free from binding mucosal sialic acids.
Stephen Withers and his team have spent decades studying the mechanisms by which enzymes like neuraminidase interact with sugars like sialic acid.
Subtypes of flu virus get their name from two proteins they carry on the surface: hemagglutinin and neuraminidase.
The other, neuraminidase, allows replicated viruses to break out of the cell and move on to the next target.
In sialidosis, lysosomal neuraminidase is deficient (N-acetyl-[alpha]-neuraminidase).
Among their perspectives are inhibiting HIV entry, helicase-primase inhibitors as a new approach to combating herpes simplex virus and varicella zoster virus, alkoxyalkyl ester pro-drugs of antiviral nucleoside phosphate and phosphonates, maribavir as a novel benzimidazole ribonucleoside for preventing and treating cytomegalovirus diseases, lethal mutagenesis as an unconventional approach to combating HIV, silencing viruses with antiviral RNAi, and neuraminidase inhibitors as anti-influenza agents.
The meta-analysis also included five observational studies and two surveys that compared the second marketed neuraminidase inhibitor, inhaled zanamivir, with no antiviral therapy in patients treated as outpatients.