nephrotoxic


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Related to nephrotoxic: ototoxic, hepatotoxic, nephromalacia
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Words related to nephrotoxic

toxic to the kidney

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The present study showed that mitomycin/capecitabine is an acceptable alternative to nephrotoxic drugs like cisplatin.
It is concluded that Cadmium is a potential nephrotoxic chemical and can lead to progressive renal failure by inducing dose-dependent pathological changes in glomeruli.
(2) This might suggest that increasing knowledge of precautions regarding nephrotoxic drugs have helped to reduce the incidence of drug induced AKI.
In 2002, the Contrast Media Safety Committee of the European Society of Urogenital Radiology concluded that according to experimental animal data, GBCA was more nephrotoxic than iodinated contrast at equivalent x-ray attenuating doses (17).
Understanding the cellular mechanisms by which the nephrotoxic aminoglycoside gentamicin activates membrane receptors and induces cellular cytotoxicity will enable future identification of aminoglycoside-sensitive targets and potential uptake blockers (14).
Therefore, renal function tests should be performed regularly to prevent further complications.6-8 Drugs which are oxidative in nature such as sulfonamides, primimaquine and nitrofurantoin should also be avoided along with nephrotoxic drugs.9
An 81-year-old white man with prior chronic kidney disease stage 3b and no prior home nephrotoxic medications presented with gross hematuria and elevated serum creatinine.
We collected the following variables: sociodemographic data, updated Charlson comorbidity index (not adjusted for age) (18), center, clinical presentation, intake of nephrotoxic treatments, results of HFRS laboratory diagnosis, date of first symptoms, date and duration of hospitalization, results of standard biological data at baseline and during hospitalization, and the occurrence of severe disease.
Risk factors previously reported to be associated with TDF-induced nephropathy include older age, (10-13) TDF exposure (14,15) comorbid conditions such as diabetes, hypertension, (10,16) underweight, (10,12) baseline CD4 <200 cells/cmm, (10,12) female gender, (12,13,17) co-infection with hepatitis C virus (HCV), (14,17) hepatitis B virus (HBV), (18) concurrent use of nephrotoxic drugs, (19) and treatment with ritonavir-boosted protease inhibitors.
It is known that toluene, xylene, and N-hexane have neurotoxic, nephrotoxic, myotoxic, and hepatotoxic effects (3).
There is also a theoretical risk that the D form of serine (produced from L-serine) may be nephrotoxic, although this has never been demonstrated with this disorder (5).
Individuals with previous history of kidney disease, use of non-steroidal antiinflammatory or other nephrotoxic drugs and any other condition that could affect kidney function were excluded.
The cornerstone of preventing CI-AKI is appropriate risk stratification, intravenous hydration, appropriate withholding of nephrotoxic medications, use of low or iso-osmolar contrast media and various intraprocedural methods for iodinated contrast dose reduction (Gupta & Bang, 2010).
In majority of cases birth asphyxia and sepsis are commonly encountered underlying conditions of AKI in these patients while other conditions in neonates associated with development of AKI may be; dehydration, bleeding, respiratory distress syndrome (RDS), congestive cardiac failure (CCF) and nephrotoxic drug.9,10