As the underlying cause was hypertensive nephrosclerosis
, it suggests that this form of ESKD is preventable with earlier intervention.
[ClickPress, Tue Jul 23 2019] The increasing geriatric population and the rising prevalence of kidney disorders like diabetic neuropathy are the major factors driving the growth of the global nephrosclerosis
In one study, angiogenesis factors in GN with different etiologies consisting of lupus nephritis were examined and showed that patients with more severe nephrosclerosis
exhibit lower expression of CD34 in the tubulointerstitium (17).
Microembolic renal ischemia, hypertension, and nephrosclerosis
. Arch Pathol.
(2010) Bone Morphogenetic Protein (BMP)-7 expression is decreased in human hypertensive nephrosclerosis
. BMC Nephrol 11: 31.
The organ recipient was a 53-year-old male with end stage renal disease secondary to hypertensive nephrosclerosis
on hemodialysis three times per week for a total duration of 52 months.
He had moderate cardiomegaly (weight = 533 grams) with marked concentric left ventricular hypertrophy and bilateral nephrosclerosis
, consistent with long-standing hypertensive cardiovascular disease.
In our data, the cause of renal failure included hypertensive nephrosclerosis
at a ratio of 32.9%, chronic glomerulonephritis at a ratio of 28.9%, polycystic disease at a ratio of 11.8%, diabetic nephropathy at a ratio equal to 9.2%, and other causes at a ratio of 17.1%.
PGIS KO mice also developed ischemic renal disorders, including nephrosclerosis
and renal infarction.
Elevated uric acid may have a role in initiating hypertension, nephrosclerosis
and insulin resistance.
The main cause of CKD in was hypertensive nephrosclerosis
in the whole cohort of patients, the cause of ESKD was associated with the RRT modality: the proportion of patients with chronic glomerulonephritis or chronic interstitial nephritis on self-care therapy was significantly higher than that of patients with nephrosclerosis
, diabetic nephropathy or unknown cause of ESKD" (p.
Jack White is a 52-year-old male living with ESKD secondary to hypertensive nephrosclerosis
caused by long-standing hypertension.
As determined in animal studies, high doses of cadmium lead to nephrosclerosis
, osteomalacia, testicular interstitial hemorrhage with edema, fetal death, and placental necrosis (Takiguchi and Yoshihara 2006; Thijssen et al.
: pathogenesis and prevalence.