Factors that adversely influenced pregnancy outcomes, including lupus nephritis
, anti-Ro/SSA antibody, anti-La/SSB antibody, C3 and C4, antiaCL antibody, recurrence of lupus, hypertension, and Raynaud's phenomenon, were analyzed using multinomial logistic regression.
While secondary glomerular disease (SGN) in our population was most commonly caused by lupus nephritis
s (NASDAQ: AUPH) (TSX: AUP) Phase 3 confirmatory clinical trial evaluating voclosporin for the treatment of lupus nephritis
, an autoimmune disease caused by lupus that involves extreme inflammation and failure of the kidneys, the company said.
studied 68 patients with biopsy proven lupus nephritis
Fisher's exact test showed that proteinuria, lupus nephritis
, vasculitis and fever in the SLEDAI are closely related to AMA positivity (p < 0.
We report a rare case with ANCA-negative pauci-immune crescentic necrotizing lupus nephritis
and briefly discuss the possible mechanism and pathogenesis.
Methods: This retrospective, observational study was conducted at the Lady Reading Hospital in collaboration with the Fauji Foundation Hospital, Peshawar, Pakistan, and comprised patient records of biopsy-proven lupus nephritis
from 1995 to 2012.
Antibodies against complement in SLE have also been evaluated in this regard and anti C1q antibody has been demonstrated to have potential diagnostic utility as a marker of lupus nephritis
and "possible activity indicator"4.
Immunofluorescence studies revealed granular deposition of IgG, IgA, IgM, C3, and C1q in the capillary wall of the glomerulus, indicative of membranous nephropathy, suggestive of class V lupus nephritis
with no chronicity.
8% (generic name: mycophenolate mofetil) for the indication of Lupus Nephritis
GlobalData's clinical trial report, "Lupus Nephritis
Global Clinical Trials Review, H1, 2016" provides an overview of Lupus Nephritis
clinical trials scenario.
is diagnosed based on a needle biopsy of the kidney.
with positive titers for ANCA spe cific for proteinase 3.
Clinical outcomes of kidney transplants on patients with end-stage renal disease secondary to lupus nephritis
, polycystic kidney disease and diabetic nephropathy
Management guidelines for HSP nephritis
in an adult remain obscure and more research is needed in this area.