Jazz Pharmaceuticals said solriamfetol (JZP-110) is a selective dopamine and norepinephrine reuptake inhibitor (DNRI) in development for the treatment of excessive sleepiness in adult patients with narcolepsy
, OSA, and Parkinson's disease.
Pipeline Products for Narcolepsy
- Comparative Analysis 9
is a rare disease caused by sleep disorder observed during the rapid eye movement (REM) phase of sleep, which is characterized by excessive sleepiness during daytime accompanied by sudden loss of muscle tonus, hallucinations while falling asleep, and sleep paralysis (1).
had led to her sleeping for up to 19 hours per day on occasions and her mental health worsened.
is a potentially disabling disorder affecting quality of life.
Additionally, the report provides an overview of key players involved in therapeutic development for Narcolepsy
and features dormant and discontinued projects.
is a neurological disorder of sleep regulation that affects the control of sleep and wakefulness.
should not cause serious or long-term health problems but it can have a significant impact on daily life.
In that state, another phenomenon that is often responsible for misdiagnosing narcolepsy
as schizophrenia begins to happen: Narcoleptics are in a dream state and have what seem to be hallucinations.
Chloe Glasson, 15, had initially been turned down but the DWP reversed their decision and agreed to pay her family up to PS537 a month to help them cope with her chronic narcolepsy
Background: Hypocretin (HCRT) signaling plays an important role in the pathogenesis of narcolepsy
and can be significantly influenced by Chinese herbal therapy.
Scientists have retracted a December 2013 study suggesting that narcolepsy
is caused by an immune attack on one's own tissues (SN: 1/25/14, p.
is a chronic neurodegenerative disease caused by autoimmune destruction of hypocretin-producing neurons.
MINNEAPOLIS -- After 12 weeks of treatment with a novel agent, narcolepsy
patients showed an 86% improvement from baseline in scores on the Clinical Global Impression-Change scale, compared with 38% of placebo patients.
22 ( ANI ): A team of scientists have associated Pandemrix - an influenza vaccination - to an increased risk of narcolepsy
in young adults.