nalidixic acid


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  • noun

Synonyms for nalidixic acid

antibacterial agent used especially to treat genitourinary infections

References in periodicals archive ?
The highest level of resistance was to ampicillin (56.1%), followed by nitrofurantoin (43.9%), tetracycline (41.4%), cefotaxime (37.8%), nalidixic acid (29.3%), ciprofloxacin (23.1%), co-trimoxazole (21.9%), meropenem (14.6%), imipenem (12.2), chloramphenicol (7.3%), gentamicin (4.9%), piperacillin-tazobactum (3.7%).
Saiwan, "Sorption of acetaminophen, 17[alpha]-ethynyl estradiol, nalidixic acid, and norfloxacin to silica, alumina, and a hydrophobic medium," Water Research, vol.
coli strains were highly resistant to cefotaxime, nalidixic acid, nitrofurantoin, gentamicin, amikacin, ciprofloxacin, and cotrimoxazole.
Biochemical tests, namely, gram staining reaction, oxidase, urease, and catalase tests, and antibiotics (cephalothin and nalidixic acid) susceptibility test were employed [14, 15].
coli that are resistant, 86% (62/72) were resistant to tetracycline, 22%, 21%, and 8% were resistant to ciprofloxacin, nalidixic acid, and chloramphenicol, respectively.
Another research of Karachi is also the evident of high rate of resistance in Shigella against Ampicillin and nalidixic Acid 55.5% and 39% respectively.12 Resistance to ampicillin and cotrimoxazole is also observed in E.coli as 72% and 78% respectively.13
In our study, most of the isolates were resistant to ampicillin, trimethoprim-sulfamethoxazole and nalidixic acid. The presence of ESBL producing genes such as blaCTX-M-1 in the study isolates further indicates the threat of spreading resistance to third-generation cephalosporins, as cephalosporins are used for treatment in children, where quinolones are usually not recommended.
The highest resistance was found against nalidixic acid (91.7%) and ampicillin (90.8%) and significant resistance was also found against sulphamethoxazole + trimethoprim (co-trimoxazole) (67.2%).
Summary: Different analogs of 1-ethyl-1, 4-dihydro-7-methyH-4-oxo-1, 8-naphthyridine-3-carbohydrazide (carbonyl hydrazone derivatives of Nalidixic acid, H 1-10) and their copper complexes have been synthesized from reaction of Nalidixic acid hydrazide with substituted benzaldehyde.
The first quinolone (quinoJ[ine] + -one [compound related to ketone]), nalidixic acid, was isolated as a byproduct of chloroquine (see "quinine," https://wwwnc.
The antibiotics tested in this study include ampicillin (10 [micro]g), cefixime (5 [micro]g), ceftriaxone (30 [micro]g), nalidixic acid (30 [micro]g), ciprofloxacin (5 [micro]g), levofloxacin (5 [micro]g), chloramphenicol (30 [micro]g), cotrimoxazole (25 [micro]g), azithromycin (15 [micro]g), and tetracycline (30 [micro]g), respectively.
There were intermediate zone of inhibition found on claforan, nalidixic acid, amoxycillin, fosfomycin, fortum, and erythromycin on Mueller Hinton's agar after 24 hours incubation.
Levofloxacin (LEV), Ciprofloxacin (CIP), Nalidixic acid (NA), 53.5% against Metabolic inhibitor (MI) category Sulphamethoxazole/ Trimethoprim (SXT), 17.8% against Cell membrane inhibitor (CMI) category i.e.