panel (Mi-2, PL-12, PL-7, EJ, OJ, Ku, SRP, U2 SnRP, Anti-PM/Scl Ab, Anti Jo-1) was negative.
Arimoclomol is in clinical development at Orphazyme for the treatment of Niemann-Pick disease Type C, Gaucher disease, sporadic Inclusion Body Myositis
, and amyotrophic lateral sclerosis.
Orphazyme A/S (CPH:ORPHA.CO), a biopharmaceutical company dedicated to developing treatments for patients living with rare diseases, announced on Tuesday full enrolment of its phase II/III trial of arimoclomol for the treatment of sporadic Inclusion Body Myositis
Gadolinium-enhanced [T.sub.1] and [T.sub.2]-weighted MRI of the orbit revealed inflammation in bilateral extraocular muscles which was more pronounced in the left medial rectus suggesting orbital myositis
(Figures 3 and 4).
A case report of acute orbital myositis
defined by the computerized tomographic scan.
Electromyography of the calf muscles showed low amplitude, polyphasic, and myopathic units, the interference pattern indicated myositis
The primary outcome was the rate of achievement of significant improvement at week 12 as defined using the validated International Myositis
Assessment and Clinical Studies (IMACS) criteria, which require at least a 20% improvement in three of six core set measures coupled with no more than two measures worsening by 25% or more.
Idiopathic inflammatory myopathies (IIMs) are heterogeneous disorders characterized by chronic muscle weakness and muscle fatigue and mononuclear cell infiltration into skeletal muscle. The most common subgroups in adults are dermatomyositis (DM), polymyositis (PM), amyopathic DM (ADM), inclusion body myositis
(IBM), and juvenile DM (JDM).
Histologically, there was moderate to severe, multifocal, degenerative myositis
with intramyofiber schizonts and minimal lymphoplasmacytic infiltrates in the proventriculus, ventriculus, heart, and skeletal muscle.
Snake venom could be a remedy to many diseases, particularly neuralgia, arthralgia, myalgia, myositis
, rheumatism, hypertension, and asthma.
In lieu of flowers, donations may be made to the Myositis
Association, 1940 Duke Street, Suite 200, Alexandria, VA 22314 or a favorite animal charity of your choice.
(13) Autoimmune conditions were diagnosed based on the classification criteria for myositis
. (14) and ILD was confirmed by histopathology or by the detection of interstitial infiltrates after chest radiography (X-ray generator, 0.6/1.2 P324DK-125, Shimadzu Corporation, Kyoto, Japan, and X-ray photoreceiver, flat panel detector CALNEO-U, Fujifilm Medical, Tokyo, Japan) or high-resolution computed tomography (CT, Aquilion ONE TSX-301C/3A, Toshiba Medical Systems Corporation, Otawara City, Tochigi-ken Japan).
Keywords: Orbital myositis
, pseudotumor orbita, sixth nerve palsy, magnetic resonance imaging
Anti-aminoacyl-tRNA synthetase syndromes (ARS) comprise a subset of patients with idiopathic inflammatory myopathy (IIM), predominantly, polymyositis (PM) and dermatomyositis (DM), and overlap myositis
. Differential diagnosis included traumatic muscle injury with hematoma, infectious myositis
ossificans, and soft tissue neoplasm.