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Related to microtubule: Intermediate filaments
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  • noun

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a microscopically small tubule

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In this article, we describe a case of bilateral maxillary sinus mucoceles that featured an absence of one of the microtubule doublets in three of the outer doublets of the axoneme, thereby establishing a diagnosis of isolated ciliary dysfunction.
To better understand the process of the simultaneous formation of the first two polar bodies in an androgenetic clam, the meiotic process was observed by visualizing cytoskeletal elements, such as microtubules and centrosomes, and distribution of actin.
Braguer, "Understanding microtubule dynamics for improved cancer therapy," Cellular and Molecular Life Sciences, vol.
Tau protein is part of the microtubule structure and plays an important role in proper neuronal functioning.
Steinmetz, "Tracking the ends: a dynamic protein network controls the fate of microtubule tips," Nature Reviews Molecular Cell Biology, vol.
Oryzalin, a microtubule inhibitor, blocks microtubule assembly but not ongoing disassembly, causing microtubule depolymerization.
In a recent work (Argiros et al., 2012), we attempted to reconcile the astral microtubule and central spindle models in echinoderm embryos by examining the requirement for, and distribution of, the centralspindlin (tracked via anti-MKLP1 localization) and CPC (tracked via anti-Survivin localization) complexes during early division cycles.
Using VND6-induced xylogenic culture, we were able to observe cortical microtubule dynamics during cell wall pit formation.
Since microtubules are involved in the transport of the androgen receptor to the nucleus, agents that target microtubule interactions with the receptor have the potential to serve an important therapeutic role in treating advanced prostate cancer.
In the studies, Anisina significantly improved the effectiveness of the standard of care microtubule targeting compound, vincristine, in an animal model of neuroblastoma.
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