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Related to microsome: microsomal enzymes
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  • noun

Words related to microsome

a tiny granule in the cytoplasm that is where protein synthesis takes place under the direction of mRNA

References in periodicals archive ?
Mutagenicity of gingerol and shagaol and antimutagenicity of zingerone in Salmonella microsome assay.
OBJECTIVES: The purposes of this study were to characterize the in vitro metabolism of 2,2',4,4'-tetrabromodiphenyl ether (BDE-47) by human liver microsomes (HLM) and recombinant human CYPs, and to identify the CYP(s) that are active in the oxidative metabolism of BDE-47.
According to Celsis, InVitroCYP is the only microsome product on the market with substrate data reported at both Km and Vmax concentrations, providing researchers with maximum visibility for predictive performance and quality.
85-fold of increase of CYP2E1 activity and sustained loss almost half of HO-1 activity in rat liver microsomes.
The Salmonella mammalian microsome mutagenicity assay has been central to the field of genetic toxicology since the 1970s.
With throughputs approaching fluorescence- or radioactivity-based methods (3500 data points per eight-hour shift on a single instrument), and full compatibility with liver microsome preparations, the RapidFire P450 inhibition assay platform enables researchers to advance lead optimization with highly accurate mass spectrometric data.
Method for the assay of microsome 1'-hydroxy midazolam concentrations was adapted from those described by our previous report (Li et al.
Human liver cytosol and microsome extracts were obtained from BD Biosciences (San Jose, CA).
Characterization of the anti-liver-kidney microsome antibody (anti-LKM1) from hepatitis C virus-positive and -negative sera.
We conducted lung microsome Western blots as previously described (Ghanem et al.
YKP3089 was well absorbed in test animals, displayed good microsome stability, and demonstrated good distribution with excellent mass balance recovery.
Purpose: Potential drug-interactions with MA via inhibition of cytochrome P450 (CYP) activity in human liver microsomes (HLMs), have not been investigated.