Aqueous exits the internal eye via the trabecular meshwork
and Schlemm's canal, often referred to as the 'conventional' outflow pathway (Figure 2).
Corticosteroids affect the function of the trabecular meshwork
by altering its cellular composition, increasing substance deposition in the meshwork
and inhibiting enzymes involved in the normal and necessary degeneration of older components of the structure by phagocytosis.
Laser coagulation of the mid-trabecular meshwork
was applied to induce ocular hypertension in the right eye (OD) of each monkey.
Recent preclinical studies have also shown that Rhopressa may have disease-modifying properties, including an anti-fibrotic effect of netarsudil on trabecular meshwork
cells and the potential to increase perfusion of the trabecular meshwork
In this condition, the angle in the eye where the iris meets the cornea is normal, but the eye's trabecular meshwork
(its drainage canals) becomes clogged over time, causing an increase in IOP and damaging the optic nerve.
By promoting autophagy, it may prevent exfoliated cells from blocking the aqueous humor drainage channels of the meshwork
and the Schlemm's canal.
Mice with glaucoma were able to maintain normal intraocular pressure after receiving a stem cell transplant to restore their eye's trabecular meshwork
The influx of cells regenerated the tiny, delicate patch of tissue known as the trabecular meshwork
, which serves as a drain for the eyes to avoid fluid buildup.
The CAQK peptide binds to components of the meshwork
surrounding brain cells called chondroitin sulfate proteoglycans.
The installation is composed of bundles of hexagonal meshwork
steel and acrylic spars that form a freestanding chamber.
The procedure involves use of a Q-switched frequency-doubled Nd:YAG laser that targets melanocytes in the trabecular meshwork
of the eye, thus reducing intraocular pressure (IOP).
Cells called cancer-associated fibroblasts arrange a normal meshwork
of fibers into straight tracks, cell biologist Begum Erdogan of Vanderbilt University in Nashville and colleagues reported December 13.
Extensive pigment release during trauma clog the trabecular meshwork
and mediate directly or indirectly causing changes in trabecular meshwork
(9, 10) which in turn may be the cause for decreased aqueous outflow by primary damage, inflammation or pigment release at trabecular meshwork
The debris in the trabecular meshwork
which consists of glycosaminoglycans is removed by the high fluid flow during aspiration.
Nuclei were loosely arranged in a meshwork
of fibrous matrix.