(18.) Akbayir N, Yildirim S, Sokmen HM, Kilic G, Alkim C Intussusception of vermiform appendix with microscopic melanosis coli
: a case report.
These diagnoses included the following: melanosis coli
(in 4 specimens with tubular adenomas and 1 specimen with hyperplastic polyp), mucosal prolapse (in 2 specimens with hyperplastic polyps), schistosomiasis (Figures 4(a), 4(b), and 4(c)) (in 1 specimen with adenocarcinoma and 1 specimen with hyperplastic polyp), and intestinal spirochetosis (Figure 5) (in 1 specimen with sessile serrated adenoma), and they were confirmed retrospectively by both of us.
Long-term use/abuse of laxatives can actually cause damage to the lining of the intestines leading to a condition called "melanosis coli
." Viewed endoscopically this condition shows the lining of the colon looking like "giraffe skin" with light and dark patches indicating laxative overuse/abuse.
It is widely known that a long-term use of anthranoid-containing laxatives is the cause of melanosis coli
, a brownish pigmentation of the colon caused by the accumulation of dark brown pigment in macrophages of the lamina propria (Capasso and Gaginella, 1997).
Some types of laxatives cause staining of the bowel walls (also called melanosis coli