Apoptotic depletion of CD4+ T cells in idiopathic CD4+ T lymphocytopenia
. J Clin Invest 1996;97(3):672-80.
Chung et al reported that lymphocytopenia
was associated with elevated interleukin levels in patients with sepsis (29).
The elevation of NLR usually means neutrophilia and lymphocytopenia
. Tumor-associated neutrophils (TANs) and other cells such as phagocytes produce a variety of cytokines and cytotoxic mediators [35-40] which play a vital role in promoting angiogenesis, stimulating DNA damage, rebuilding the extracellular matrix (ECM) to facilitate invasion, and evading host defense mechanisms.
She was diagnosed a month earlier with SLE after she presented with a photosensitive rash, arthritis, anemia, lymphocytopenia
, albuminuria, hematuria, and positive antinuclear antibodies.
Initial laboratory results were only notable for a hemoglobin of 10.0 mg/dl, a mild relative lymphocytopenia
with a normal white blood cell count.
Our patient also had many of the studied risk factors to develop Aspergillus endophthalmitis such as immunocompromise, neutropenia, lymphocytopenia
, and malignancy .
mucogenicum infections of the central nervous system in immunocompetent hosts, skin lesions in the presence of the tumor necrosis factor-[alpha] antagonist etanercept, peritonitis associated with peritoneal dialysis, bacteremia in patients with hepatitis B and D associated cirrhosis with negative ascites fluid cultures, bone marrow involvement with retinal lesions and acute respiratory distress in a patient with idiopathic CD4+ T lymphocytopenia
, and wound infections .
Hematology and coagulation studies showed hemoglobin of 12.9 g/dL (12.5-15.5 g/dL), thrombocytopenia (platelet count of 55,000; 150,000-400,000 normal), neutrophilia (79.7%; normal range 37-73%), monocytosis (13.3%; normal range 3.0-10%), lymphocytopenia
(6.3%; normal range 20-55%), high red cell distribution width of 19.7% (11.0-15.6%), and elevated activated partial thromboplastin time of 39 seconds (normal range 26-34 seconds).
Haematological evaluation of some excipients has shown them to be associated with erythrocyte destruction and the potential for haemolysis, incidences of leucopenia and lymphocytopenia
, leukaemia , and a reduction in haemoglobin and haematocrit after administration of some solubilizing enhancing agents .
Patients with an increased NLR exhibit relative lymphocytopenia
, which can lead to worse prognosis and an increased potential for tumor progression.
has also been established as a diagnostic marker of bacterial infection.
and neutrophil-lymphocyte count ratio predict bacteremia better than conventional infection markers in an emergency care unit," Critical Care, vol.
As far as laboratory test results are concerned, statistically significant differences (Mann-Whitney U test) between patients with pSS and the control group were noted in anaemia rate (p = 0.0085), lymphocytopenia
(p = 0.0006), ERS level (p = 0.001), and in RF titer (p < 0.00001).
A venous blood sample was collected and submitted for hematologic evaluation, results of which showed hemoconcentration (suspected to be the result of dehydration), anemia, and leukopenia with a slight monocytosis and lymphocytopenia
high-intensity exercise) results in a much smaller level of post-exercise leukocytosis, lymphocytosis, and neutrophilia and a less-pronounced lymphocytopenia