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  • noun

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skin disorder characterized by patchy bluish discolorations on the skin

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APA-associated cardiac valve disease APA-associated livedo reticularis APA-associated nephropathy APA-associated thrombocytopenia Other skin manifestions Ulcerations, pseudo-vasculitic lesions, digital gangrene, superficial phlebitis, malignant atrophic papulosis-like lesions, subungual splinter hemorrhages, and anetoderma (a circumscribed area of loss of dermal elastic tissue) Other neurological manifestations Cognitive dysfunction, chorea, headache or migraine, multiple sclerosis, transverse myelopathy, and epilepsy Table 4.
5) Skin involvement occurred in 35% of these patients including livedo reticularis, gangrene and cyanotic toes.
Livedo reticularis, for which there is no specific therapy, was the most common skin manifestation, with 36 of the 200 patients appearing with it and 51 of the patients showing it by the end of follow-up.
Features of APS include hemolytic anemia, thrombocytopenia, venous and arterial occlusions, livedo reticularis, pulmonary manifestations, recurrent fetal loss, neurologic manifestations (stroke, transverse myelitis, Guillain-Barre syndrome); and a positive Coombs test, anticardiolipin antibodies, or lupus anticoagulant activity (1).
Adverse effects occur in fewer than 10% of patients;[2] they include some anticholinergic effects, ankle edema and livedo reticularis (purplish mottling of the skin, which resolves on discontinuation of the drug).
In addition, no data indicate efficacy of warfarin in treatment of microangiopathic nephropathy, valvular heart disease, livedo reticularis, or leg ulcers.
Primary hyperoxaluria: report of a patient with livedo reticularis and digital infarcts.
Other common associated manifestations include livedo reticularis, thrombocytopenia, valvular heart disease, and nephropathy with renal insufficiency, hypertension, and proteinuria.
No obvious pathological changes could be detected in 19 of 26 patients (15 primary, 11 SLE-related) with livedo reticularis who underwent two skin biopsies each "despite a very uniform standardization of the biopsies," Dr.
SAN FRANCISCO -- It's no secret that livedo reticularis can be a symptom of antiphospholipid syndrome, yet many clinicians still miss the diagnostic implications of this peculiar rash, Dr.
Skin lesions of rheumatoid arthritis are seen as rheumatoid nodules, arteritis, palmar erythema, vasculitis, purpuric or necrotic skin lesions, livedo reticularis, and pyoderma gangrenosum (8).
Abstract: Livedo reticularis is a common presentation of the anticardiolipin syndrome.
CLINICAL FEATURES AND ROC ANALYSIS OF RAW DATA Of the 144 patients in our study, 25 had recurrent venous thromboembolism, 21 had peripheral arterial occlusions, 10 had ulcerations of the legs, 8 had livedo reticularis, and 37 had ischemic neurologic symptoms or signs together with radiologic evidence of cerebral vessel occlusions.
In the clinical presentation of CPX, skin lesions appear suddenly as painful, indurated nodules, which may be associated with or preceded by livedo reticularis or bullae.