(redirected from light chain disease)
Also found in: Dictionary, Medical, Legal, Financial, Encyclopedia.
Related to light chain disease: kappa light chain, LCDD
Graphic Thesaurus  🔍
Display ON
Animation ON
  • all
  • noun
  • verb

Synonyms for chain

Synonyms for chain

something that physically confines the legs or arms

a number of things placed or occurring one after the other

to restrict the activity or free movement of

Synonyms for chain

a series of things depending on each other as if linked together

(chemistry) a series of linked atoms (generally in an organic molecule)

(business) a number of similar establishments (stores or restaurants or banks or hotels or theaters) under one ownership

anything that acts as a restraint

Related Words

British biochemist (born in Germany) who isolated and purified penicillin, which had been discovered in 1928 by Sir Alexander Fleming (1906-1979)

a linked or connected series of objects

Related Words

a necklace made by a stringing objects together


Related Words

connect or arrange into a chain by linking

fasten or secure with chains

Related Words


References in periodicals archive ?
SPEP without a distinct monoclonal band in the [beta] or [gamma] region and monoclonal light chains on serum or urine immunofixation without a corresponding IgA, IgG, or IgM component are consistent with both light chain disease and IgD myeloma, and should prompt immunofixation for IgD.
We studied a 62-year-old man with light chain disease (multiple myeloma) whose urine protein electrophoresis (UPE; electrophoresis performed on agarose gel on a Panagel high resolution electrophoresis system; gel was stained with Amido Black) showed >15 narrow bands in the [beta]- and [gamma]-globulin regions; many of the bands were strongly stained and equidistant (Fig.
In the discussion of the workup of hypogammaglobulinemia, one could argue that urine immunofixation and not urine protein electrophoresis should be ordered to exclude the possibility of light chain disease.
Small quantities of monoclonal components in serum may signify light chain disease, a B-lymphocytic lymphoma or leukemia, amyloid AL (amyloidosis associated with immunoglobulin light chains), a neuropathy, or the predisposition to develop a malignant plasma cell/B-lymphocyte proliferative disorder in a patient with no currently evident clinical problem (monoclonal gammopathy of undetermined significance-MGUS).
The serum monoclonal immunoglobulins identified by IFE were IgG, n = 34; IgA, n = 11; and IgD, n = 1; there was one case of light chain disease.