(redirected from light chain)
Also found in: Dictionary, Medical, Legal, Financial, Encyclopedia, Wikipedia.
Related to light chain: Myosin light chain kinase
Graphic Thesaurus  🔍
Display ON
Animation ON
  • all
  • noun
  • verb

Synonyms for chain

Synonyms for chain

something that physically confines the legs or arms

a number of things placed or occurring one after the other

to restrict the activity or free movement of

Synonyms for chain

a series of things depending on each other as if linked together

(chemistry) a series of linked atoms (generally in an organic molecule)

(business) a number of similar establishments (stores or restaurants or banks or hotels or theaters) under one ownership

anything that acts as a restraint

Related Words

British biochemist (born in Germany) who isolated and purified penicillin, which had been discovered in 1928 by Sir Alexander Fleming (1906-1979)

a linked or connected series of objects

Related Words

a necklace made by a stringing objects together


Related Words

connect or arrange into a chain by linking

fasten or secure with chains

Related Words


References in periodicals archive ?
The immunodiagnostic tests recommended by the International Myeloma Working Group (IMWG) for the initial symptomatic screening of patients for suspected monoclonal gammopathy such as multiple myeloma include serum protein electrophoresis (SPEP), serum immunofixation, and serum free light chains (free kappa and free lambda with ratio).
Pulmonary light chain deposition disease: report of five cases and review of the literature.
2005) On the optimal ratio of heavy to light chain genes for efficient recombinant antibody production by CHO cells.
By omitting the reducing step after capturing immunoglobulins with antisera to [kappa] and [lambda] light chains, they have essentially developed an MS version of the serum free light chain immunoassay, made specific for monoclonal free light chain by visual inspection of the mass spectra (9).
Serum-free light chain assessment in hepatitis C virus-related lymphoproliferative disorders.
Cogne, "Role of light chain variable region in myeloma with light chain deposition disease: evidence from an experimental model," Blood, vol.
Serum free light chains in the diagnosis and monitoring of patients with plasma cell dyscrasias.
TeNT is produced as a single polypeptide (approximately 150 kDa) and subsequently cleaved to a two-chain active holotoxin, in which a 50 kDa N-terminal Light Chain (LC) and a 100 kDa C-terminal Heavy Chain (HC) are linked by a single disulphide bond 3'4.
While overt biclonal myeloma with obvious light chain restriction is well described, (18) to our knowledge a case of "oligosecretory" biclonal myeloma detectable only by PCR is not, prompting this report.
Another important role of the myosin light chain is regulatory function.
This peptide, made by Fmoc Chemistry (Ansynth, Roosendaal, the Netherlands), inhibits free light chain activity but "does not interfere with IgE-or IgG-mediated mast cell activation.
Monoclonal immunoglobulin deposition diseases (MIDD) include primary and light chain deposition disease.
Polyclonal B cell hyperactivity, hypersecretion of antibodies and also increased local synthesis may be responsible for the increase in free light chain levels in relation to disease activity or relapses of disease.
Chapters address identification of amyloid fibrils, in vivo imaging of amyloid fibrils, diagnosis and classification, pathogenesis of systemic amyloidosis, supportive care, response assessment and prognosis in evaluating patients with immunoglobin light chain amyloidosis, amyloid heart disease, amyloid neuropathy, treatment of immunoglobin light chain amyloidosis, high dose therapy with stem cell replacement, transthyretin amyloidosis, and rare forms of amyloidosis.