leflunomide


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Synonyms for leflunomide

an anti-TNF compound (trade name Arava) that is given orally

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EULAR responses at 6 months were analyzed for 9 medications (as combination or monotherapy): methotrexate, hydroxychloroquine, leflunomide, sulfasalazine, etanercept, adalimumab, tocilizumab, abatacept, and rituximab, with the remaining medications not having sufficient data to record a EULAR response (Table 4).
Methotrexate therapy was associated with absence of ATI development at W22 compared to other csDMARDs (leflunomide or hydroxychloroquine) ([chi square] = 6.13; p = 0.0133).
Based on the report of Henao-Martinez on the successful use of leflunomide in an HIV patient with HSV-2 proctitis [7], leflunomide 20 mg orally twice daily was then started; intravenous foscarnet and topical imiquimod were continued.
294 patients with active RA (DAS28>5.1) were randomized via lottery methods to Leflunomide 20mg daily (n=147) and Methotrexate (n=147).
Healthcare company Sanofi (EURONEXT:SAN) (NYSE:SNY) revealed on Thursday that it has launched the approved generic version of Arava (Leflunomide tablets) 10 mg tablets through its US generics division, Winthrop.
They were all given leflunomide to observe the clinical outcomes and whether HBV was activated.
Leflunomide, which is currently used for the treatment of rheumatoid arthritis, has also been used as an adjunctive therapy for the treatment of BK viruria and viremia.
Leflunomide-induced pneumonitis (LEIP) usually occurs within the first 20 weeks of initiation of leflunomide, usually in patients with history of rheumatoid arthritis and either exposure to methotrexate or interstitial lung disease or both.
After 3 months with increased dose of MTX, the patient was still presenting the active form of PsA, therefore leflunomide 20 mg per day (oral administration) was added to the medical treatment.
Objective To compare the effectiveness and safety of leflunomide with methotrexate (MTX) in the treatment of psoriatic arthritis.
Therapy preceding the illness included long-term methotrexate (20 mg weekly); leflunomide (20 mg/d), which was stopped 1 week before he sought care at a hospital; prednisone (5 mg/d); etanercept (antitumor necrosis factor a therapy) for 5 months; and nonsteroidal anti-inflammatory drugs (NSAIDs).
-- Leflunomide must be withdrawn at least 8 weeks prior to Day 1 or a minimum of 2 weeks prior to Day 1 if after 11 days of standard cholestyramine washout.
A study examining methotrexate and leflunomide reported an unprecedented ACR Pedi 70 response in 86% of poly-JIA patients taking methotrexate after 2 years of open-label medication.
The compound eventually was developed into the drug leflunomide, which was approved to treat rheumatoid arthritis, another disease that involves immune attacks.