leflunomide


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Synonyms for leflunomide

an anti-TNF compound (trade name Arava) that is given orally

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References in periodicals archive ?
Keywords: Methotrexate, Rheumatoid arthritis, Safety, Leflunomide.
Therefore, in a multicenter, prospective, double-dummy randomized clinical trial (RCT), we evaluated the efficacy and safety of the angiotensin receptor blocker (ARB) telmisartan in combination with the antiplatelet drug clopidogrel, the immunosuppressant leflunomide, or both drugs for managing IgAN.
1) were randomized via lottery methods to Leflunomide 20mg daily (n=147) and Methotrexate (n=147).
5-20 Leflunomide 34 34 Sulfasalazine 16 16 Hydroxychloroquine 7 7 bDMARD 19 19 csDMARD combination 20 20 Remission/LDA (n=51) n % Median Range Methyl prednisolone 18 35 Glucocorticoid dosage (mg/day) 4 1-8 Methotrexate use 28 55 Methotrexate dosage (mg/week) 10 7.
Concurrent antiviral and immunosuppressive activities of leflunomide in vivo.
Objective: To study the clinical outcomes of low-dose leflunomide for rheumatoid arthritis (RA) complicated with hepatitis B virus (HBV) carriage and to observe the safety.
Agents such as fluroquinolone antibiotics, intravenous immune globulin (IVIG), leflunomide, and cidofovir may be used (Ginevir et al 2007; Jacobi et al, 2013; Johnston et al, 2010; Rinaldo et al, 2013; Sawinski & Goral, 2014; Sood et al.
Severe infections following leflunomide therapy for rheumatoid arthritis.
Leflunomide-induced pneumonitis (LEIP) usually occurs within the first 20 weeks of initiation of leflunomide, usually in patients with history of rheumatoid arthritis and either exposure to methotrexate or interstitial lung disease or both.
After 3 months with increased dose of MTX, the patient was still presenting the active form of PsA, therefore leflunomide 20 mg per day (oral administration) was added to the medical treatment.
34) DOCGL distinguishes active from control treatments in randomized controlled clinical trials of methotrexate, (35) leflunomide, (36) abatacept, (37) adalimumab, (38) and certolizumab, (39) generally at levels of significance as high as or higher than any of the other 6 RA core data set measures, including joint counts and laboratory acute phase reactants.
Objective To compare the effectiveness and safety of leflunomide with methotrexate (MTX) in the treatment of psoriatic arthritis.
Therapy preceding the illness included long-term methotrexate (20 mg weekly); leflunomide (20 mg/d), which was stopped 1 week before he sought care at a hospital; prednisone (5 mg/d); etanercept (antitumor necrosis factor a therapy) for 5 months; and nonsteroidal anti-inflammatory drugs (NSAIDs).
Leflunomide must be withdrawn at least 8 weeks prior to Day 1 or a minimum of 2 weeks prior to Day 1 if after 11 days of standard cholestyramine washout.
The compound eventually was developed into the drug leflunomide, which was approved to treat rheumatoid arthritis, another disease that involves immune attacks.