Patients with pachyonychia congenita (type 2) also may have EVHC as part of their presentation, but this patient does not have nail dystrophy, focal palmoplantar tar keratoderma
, follicular keratoses, or multiple steatocysts, which also are features of this condition.
Upon physical examination, the patient had circumscribed, well-defined, scaling salmon plaques, distributed symmetrically on the elbows, knees, and dorsal aspects of the hands and feet, along with an orange keratoderma
On examination, there were diffuse erythematous infiltrated papules coalescing into plaques involving the trunk, bilateral shoulders and extending to lower extremities, in addition to the previous keratoderma
climactericum is a hyperkeratosis of the soles which slowly develops in the heel and forefoot area and develops into non-itchy, hyperkeratotic plaques which subsequently fissure and become painful.
He had frequent hospitalizations because of skin infection and fever, recurrent febrile convulsions and follow-up with a diagnosis of keratoderma
in dermatology clinics where he was referred because of skin lesions in his personal history.
Steatocystoma multiplex can be associated with pachyonychia congenita type 2 (which is characterized by hypertrophic nail dystrophy, focal keratoderma
, multiple pilosebaceous cysts, and myriad conditions associated with ectodermal dysplasia) or eruptive vellus hair cysts [1,5].
Multiple myeloma in a patient with systemic lupus erythematosus, myasthenia gravis and non-familial diffuse palmoplantar keratoderma
Known cases of colloidon baby include icthyosis vulgaris and trichothiodoystrophy, less well documented causes include sjogren -lorsen syndrome, netherton syndrome, gaucher disease type 2, congenital hypothyroidism, conradi syndrome, dorfmann-chanonin syndrome, ketoadipiaciduria, icthyosis variegata and palmoplantar keratoderma
with anogenital leukokeratosis.
Diffuse non-epidermolytic palmoplantar keratoderma
(NEPPK) is a rare condition in which individuals have thickened, yellowish skin over their palms and soles, thickened nails and suffer from excessive sweating.
Multiple epithelioma cuniculatum in a multilating keratoderma
3,4 The associated features are ectropion, scarring alopecia and palmoplantar keratoderma
The nonepidermolytic keratoderma
appears during the first years of life and involves mainly pressure areas in the palms and soles.
Carcinoma cuniculatum arising in focal plantar keratoderma
The team of scientists from A*STAR's Institute of Medical Biology (IMB), in collaboration with hospitals and research centres from the UK, Japan and Tunisia, found that this skin disorder, called punctate palmoplantar keratoderma
(punctate PPK), is caused by mutations in the AAGAB gene.
Dermatolojik muayenede yuz, boyun ve ekstremitelerde daha belirgin olan hipo ve hiperpigmente makullerin olusturdugu retikuler diskromik poikiloderma (Resim 1), govde, ekstremite ve el-ayak dorsal yuzlerinde atrofi, el parmaklari arasinda proksimal perdelenme, el-ayak basparmak tirnaklarinda subungal hiperkeratoz ve sari renk degisikligi, diffuz palmoplantar keratoderma
ve fleksiyon kontrakturu saptandi (Resim 2).