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Related to isoflurane: Desflurane
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(13) demonstrated that sevoflurane and isoflurane cause bronchodilation in patients with COPD undergoing thoracic surgery.
* Children with a history of allergy to midazolam, fentanyl, propofol, atracurium, isoflurane and Dexmedetomidine were excluded from the study.
Isoflurane is the gas that we use to maintain an anaesthetic after the anaesthetic has been induced.
Isoflurane, as expected, was superior to halothane in both maintenance and anesthetic recovery time (p<0.05).
Procedures: In phase 1, anesthesia was induced and maintained with isoflurane; intermittent positive-pressure ventilation was provided.
Conclusion: One lung ventilation may predispose to increase of intrapulmonary shunt and decrease in arterial partial pressure of oxygen; isoflurane inhalation anesthesia is more likely to cause intrapulmonary shunt, but no changes in arterial partial pressure of oxygen.
Amongst the halogenated agents new and relatively more expensive agents like isoflurane and desflurane have lost popularity in peadiatric anaesthesia, for being severely irritant to airways12.
Heart rate, blood pressure and saturation of oxygen were decreased in both groups but this decline was significantly lesser (P<0.05) in isoflurane administered group compared to xylazine-ketamine administered group.
We previously demonstrated that isoflurane and enflurane inhibit neural cell proliferation in vitro, whereas sevoflurane was much less antiproliferative [19].
It is common in a clinical setting that combined isoflurane with oxygen is applied for anesthesia of operation patients.
The average concentration of isoflurane used in Group CL was from 0.44% to o.61% which was started after intubation and stopped as soon as C[O.sub.2] was released.
Anesthesia was maintained with Isoflurane (2%) and oxygen mixture.
It is known that the newer drug sevoflurane has some chemical advantages over isoflurane (e.g., less solubility resulting in a faster onset and offset of action, less irritating to the airway, and being not as pungent as isoflurane; thus it can be used for inhalational induction of anesthesia [1, 6].
Sevoflurane, isoflurane and desflurane are the most frequently administered inhalational anesthetics.