To find the variations in OGT between European and Chinese pig breeds, attempts were made to amplify across several relatively short introns
, including intron
20 of OGT, based on the porcine OGT cDNA sequence (GenBank accession no.
3 VNTR variant in the XRCC4 gene showed an association with RA patients while no association was identified between the eNOS and RA.
Examining the set of 7 unique identified novel HLA-A alleles, polymorphisms were found within intron
1 (n = 1), intron
3 (n = 3), intron
5 (n = 1), and intron
6 (n = 2).
The presence of the intron
22 inversion was investigated using a touchdown inverse PCR method, as previously described (11).
In another study, one SNP (T204C) was observed in exon 2 and flanking intron
in buffalo dams (13).
The size of CD36 gene in each taxa and relative size of exon and intron
are shown in Fig.
A is a recombinant version of naturally occurring alpha interferon, which has been shown to exert both antiviral and immunomodulatory effects.
The sustained response rate increases from 12% with Intron
alone to 41% when ribavirin is added, so it would seem logical that it would help to add ribavirin to PEG-Intron
Group I intron
encoded endonuclease site" is interpreted to mean a segment of DNA having a sequence that is recognized by a Group I intron
encoded endonuclease and, as shown in Figure 6 of the '605 patent, that includes the insertion site for the corresponding Group I intron
We demonstrated that the first intron
of the porcine [beta]-casein gene contains a transcriptional promoter/enhancer sequence and that lactogenic expression of the porcine [beta]-casein gene was probably regulated by the first intron
But we saw the RNA molecule flexing on its own, with the intron
folding and unfolding in a way that brings the exons closer together, suggesting a more active role for introns
," Nature quoted Walter as saying.
To test amplification efficiency, we compared quantification cycle (Cq) values for samples homozygous for intron
14 polymorphism c.
Geron Corporation (Menlo Park, CA) and University of Rochester (Rochester, NY) have patented a method of inhibiting the self-splicing of a Group I intron
Patients were randomized to receive subcutaneous injections of INTRON
A 3 million international units (MIU) three times per week and either oral REBETOL 1,000-1,200 mg or a matched placebo daily for 24 or 48 weeks followed by 24 weeks of off-therapy follow up.
Palumbi of the University of Hawaii in Honolulu warns that the smaller intron
size in birds might not have evolved in connection with flight.