This multicenter, open-label trial randomly assigned 467 advanced HIV-infected patients, who progressed while taking AZT or who were intolerant
of AZT and had CD4 cell counts of 300 cells/mm3 or less (median 37) or a diagnosis of AIDS, to treatment with either ddI (didanosine) 500 mg per day or HIVID(R), 2.
Based on the data presented, the committee felt that the drug is likely to provide clinical benefits to adult AIDS patients with advanced HIV infection who are intolerant
of or who deteriorate clinically or immunologically on the other approved antiviral therapies.
ZERIT is the first new anti-HIV drug to reach the market in the United States in nearly two years, giving physicians and other health care providers an additional therapeutic option for their patients who are intolerant
to, or not benefiting from, other approved therapies.
On February 12, 2004, the FDA approved ERBITUX for use in combination with irinotecan in the treatment of patients with EGFR-expressing, metastatic colorectal cancer who are refractory to irinotecan-based chemotherapy and for use as a single agent in the treatment of patients with EGFR-expressing, metastatic colorectal cancer who are intolerant
to irinotecan-based chemotherapy.
The product was recommended for approval by 11 of the 12 EU countries for adjunctive treatment of seizures associated with Lennox-Gastaut syndrome in children and adults uncontrolled by or intolerant
to conventional anti-epileptic drugs.
Food and Drug Administration (FDA) has approved ERBITUX(TM) (Cetuximab) Injection for use in combination with irinotecan in the treatment of patients with EGFR-expressing, metastatic colorectal cancer who are refractory to irinotecan-based chemotherapy and for use as a single agent in the treatment of patients with EGFR-expressing, metastatic colorectal cancer who are intolerant
to irinotecan-based chemotherapy.
Parallel Track Program, Bristol-Myers Squibb makes ZERIT available at no charge to patients with advanced HIV infection who have failed, are intolerant
of or who have major contraindications to therapy with VIDEX and AZT.
If you are among the 75 percent of African Americans, 40 percent of Middle Easterners, the 60 to 80 percent of Ashkenazai Jewish-Americans and approximately 90 percent of Asian-Americans that are lactose intolerant
, the traditional Thanksgiving feast has traditionally meant slim pickings for you.
Ticlid is appropriate second-line therapy only for male patients who have experienced a stroke warning sign; however, if these patients are intolerant
to aspirin, Ticlid is appropriate first-line therapy.
Alibek further stated, "the only people this product won't work on is people who have been misdiagnosed as lactose intolerant
, which is a common problem.
NEW YORK, May 13, 1992 -- Many Americans believe they are allergic to dairy products such as milk and cheese when in fact they are really lactose intolerant
, said Ann Coulston, senior research dietitian at Stanford University, during a luncheon presentation to food authorities at New York's Doral Park Avenue.
Like many children his age, he was also intolerant
of glasses and contact lenses.
ABELCET, a long-standing antifungal therapy is approved for the treatment of invasive fungal infections in patients who are refractory to, or intolerant
of conventional amphotericin B.
Research released on January 21 reveals that the majority of Americans claiming to be lactose intolerant
have not been diagnosed by a doctor, or any other medical professional.
In addition to the Merck KGaA study in Europe, the program includes an ongoing Phase II clinical trial of ERBITUX monotherapy in patients with colorectal cancer who are refractory or intolerant
to chemotherapy, and two proposed Phase III randomized clinical trials in patients with second-line metastatic colorectal cancer.