The RISE-IIP study is of great importance as it evaluates riociguat in a broad range of patients suffering from pulmonary hypertension (PH) associated with idiopathic interstitial pneumonia
(IIP) a group of patients where no approved treatment is available, said Principal Investigator Dr.
The histological pattern in virus infection relies on morphological evidence of different degrees of lung injury affecting cellular pulmonary elements, resulting in interstitial pneumonia
, currently associated with classical viral inclusion (CVI).
Although lung involvement in Kawasaki disease is a rare clinical finding, interstitial pneumonia
is found in 3090% of the patients at autopsy (6,7).
In one Japanese study of 57 patients with rheumatoid arthritis, 47 with systemic sclerosis, 21 with polymyositis/derrnatomyositis, and 18 with systemic lupus erythematosus, KL-6 was found to be a useful marker for diagnosis and evaluation of interstitial pneumonia
activity associated with collagen diseases.
29,39,206-208) Other smoking-related lung changes including chronic bronchitis, emphysema, and desquamative interstitial pneumonia
may be present along with membranous bronchiolitis and respiratory bronchiolitis.
Diffuse alveolar damage in which no known causative etiology can be elucidated is clinically termed acute interstitial pneumonia
, which also corresponds to cases historically referred to as Hamman-Rich syndrome.
Tissue asbestos analysis is not necessary in cases with classic histologic features of usual interstitial pneumonia
(ie, honeycomb changes, fibroblastic foci, and absence of asbestos bodies).
Josef Vanek at Karls-Universitat in Praha, Czechoslovakia, reported his study of lung sections from 16 children with interstitial pneumonia
and demonstrated that the disease was caused by P carinii (4).
When asbestosis is symptomatic and progressive, the clinical features are essentially identical to those encountered with other forms of diffuse interstitial lung disease, such as usual interstitial pneumonia
(UIP), taking the form of an insidious onset of breathlessness and dry cough.
Based on increased awareness in the entities of idiopathic interstitial pneumonia
among pulmonologists, the true incidence and prevalence of idiopathic pulmonary fibrosis and interstitial pneumonias
is likely to be significantly higher than this study suggests.
Other lesions present in both frogs included mild to moderate lymphohistiocytic interstitial pneumonia
and mild lymphocytic interstitial nephritis.
Yousem (9) made the point that the smoker's macrophages, the radiating distribution of the lesions, the dense lamellar collagen, and the desquamative interstitial pneumonia
-like areas were not typical of nonspecific interstitial pneumonia
, and, most important, the prognosis was considerably better than that of fibrotic nonspecific interstitial pneumonia
The patient was severely hypoxic, and a repeated chest radiograph showed bilateral interstitial pneumonia
H3N2 influenza causes cough, fever, lack of appetite, weight loss and interstitial pneumonia
and can be fatal.
Chronic interstitial pneumonitis is a heterogeneous group of diseases, among which, usual interstitial pneumonia
(UIP) is common, comprising 47% to 71% of cases.