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A physiologic elevation of LDL cholesterol occurs with both omega-3 fatty acids and fibrates as lipoprotein lipase metabolizes VLDL particles secreted by the liver, removing triglycerides, shrinking the molecule into intermediate-density lipoprotein (IDL) and low density lipoprotein (LDL).
Because particles of LDL, intermediate-density lipoprotein (IDL) and VLDL each contain one apolipoprotein B (ApoB) protein, ApoB concentration may give a better indication of large lipoprotein particle concentration than measurements of cholesterol concentrations alone.
* Measurement of lipoprotein subclasses, which include HDL2 and HDL3, intermediate-density lipoprotein (IDL), very-low-density lipoproteins (VLDL1, VLDL2, VLDL3), and lipoprotein(a) [Lp(a)], a particularly dangerous lipoprotein that can lead to heart attacks and strokes.
Levels of LDL, intermediate-density lipoprotein (IDL), and very-low-density lipoprotein (VLDL) must be measured in the fasting state to be accurate, but nonfasting levels of HDL and total cholesterol generally are accurate.
Two subfractions of LDL also exist: intermediate-density lipoprotein (IDL) and lipoprotein(a).
The guidelines include a few additional situations that require treatment in adolescents: Patients should be treated with a statin and lifestyle changes even if they have a serum cholesterol level that's below 130 mg/dL if their serum triglyceride level is at or above 200 mg/dL and if their serum level of non-HDL cholesterol (LDL plus very-low-density-lipoprotein, plus intermediate-density lipoprotein cholesterol) is 160 mg/dL or higher.
(31.) Ikewaki K, Schaefer JR, Frischmann ME, Okubo K, Hosoya T, Mochizuki S, Dieplinger B, Trenkwalder E, Schweer H, Kronenberg F, Koenig P, Dieplinger H: Delayed in vivo Catabolism of intermediate-density lipoprotein and low density lipoprotein in hemodialysis patients as potential cause of premature atherosclerosis.
SBo induced a decreasing trend in the serum total, intermediate-density lipoprotein (IDL) and low-density lipoprotein (LDL) cholesterol, and subfractions of IDL and LDL in group B.
Included in the broad cut are intermediate-density lipoprotein (IDL), VLDL remnants, the main component of LDL with density 1.019 kg/L to 1.063 kg/L, and some lipoprotein(a).
First, our study on the qualitative determination of triglyceride hydroperoxide in VLDL, intermediate-density lipoprotein, and human plasma with an Orbitrap mass spectrometer, which was conducted under supervision of my professors Hitoshi Chiba and Shu-Ping Hui, was recognized as a National Academy of Clinical Biochemistry Distinguished Abstract for presentation.
In addition, apo B-l00 is associated with intermediate-density lipoprotein (IDL), VLDL, and LDL.
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