Xuan et al., "Can the upper inner side of the thigh become a new option for insulin injection?," Current Medical Research and Opinion, vol.
Kato, "Insulin binds to type V collagen with retention of mitogenic activity," Experimental Cell Research, vol.
According to the Addressing the Challenge and Constraints of Insulin Sources and Supply (ACCISS): 2016 report, the insulin market including human recombinant insulin largely contributes around 40 local manufacturers, with largely local markets apart from three largest global insulin manufactures: Novo Nordisk A/S, Sanofi S.A.
Moreover, rising diabetes population, worldwide combined with increasing research and development (R&D) activities by various government and private organizations in human insulin development is expected to boost growth of the human recombinant insulin market in the near future.
Weight gain is the primary cause behind insulin resistance, especially visceral fat around the belly that releases fatty acids into the bloodstream and inflammatory hormones as well.
While low insulin sensitivity causes insulin resistance, physical activity spurs higher insulin sensitivity, thus increasing insulin resistance correspondingly.
Multiple patient's related factors are involved which result in patients non-adherence and decreased compliance to insulin therapy which can be in the form of either missing the dose or not taking the proper dose5.
All these effects due to non-adherence to insulin has worse economical impact on the patients as well as the health care system.
more expensive than oral medications?###102###46###138###14###0.000
forms the cornerstone of treatment in T1DM.
In a survey of insulin
homeostasis in 684 patients (506 of them with known T2D, (Table 3) in the general New York metropolitan area, the authors and colleagues reported a prevalence rate of hyperinsulinism in 75.1%.
Among them, eighty-five nurses working in Operation Theater, Pediatric ward, Neonatal Intensive Care Unit, Pediatric Intensive Care Unit, and Emergency Department were excluded because these nurses do not usually administer insulin
subcutaneously using insulin
Assessment of his insulin
injection technique by a registered pharmacist revealed that the patient was using a single insulin
pen (HumaPen Ergo II) for two different insulin
preparations (Huminsulin 30/70 and Glaritus) without considering priming and compatibility of the insulin
pen for two different cartridges.