inosine


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Related to inosine: inosine pranobex
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Words related to inosine

a nucleoside that is formed by the deamination of adenosine

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Concentration in urine, [micro]mol/mmol creatinine Metabolite NMR HPLC Metabolic defect Allopurinol 630 1007 Molybdenum cofactor Deoxyadenosine 205 185/167 (b) ADA Deoxyguanosine 322 177 PNP Deoxyinosine 522 333 PNP Guanosine 588 490 PNP Hypoxanthine 271 194 Xanthine oxidase 227 171 Xanthine oxidase 22 14/47 (b) Molybdenum cofactor 1022 1048 HGPRT Inosine 1110 523 PNP SAICA-riboside 214 298 Adenylosuccinate lyase 162 126 Adenylosuccinate lyase Succinyladenosine 188 283 Adenylosuccinate lyase 101 157 Adenylosuccinate lyase Thymine 335 54 Dihydropyrimidine dehydrogenase Uracil 626 342 Dihydropyrimidine dehydrogenase Xanthine 229 182 XDH 843 794 XDH 431 286/643 (b) Molybdenum cofactor 358 957 HGPRT (a) HPLC values were not measured simultaneously with the NMR values (see Results).
Recently, the Company developed a high concentration formulation of Inosine for intravenous administration.
3) Nonstandard abbreviations: PD, pharmacodynamics; CsA, cyclosporine; AZA, azathioprine; MMF, mycophenolate mofefil; RAPA, rapamycin; CN, calcineurin; PBL, peripheral blood lymphocytes; PP1, PP2A, PP2C, protein phosphatases 1, 2A, and 2C; GVHD, graft vs host disease; 6-MP, 6-mercaptopurine; TPMT, thiopurine methyltransferase; MPA, mycophenolic acid; IMPDH, inosine monophosphate dehydrogenase.
Biochemically directed therapy of leukemia with tiazofurin, a selective blocker of inosine 5'-monophosphate dehydrogenase activity.
AVN944 is an oral small molecule drug candidate that inhibits inosine monosphospate dehydrogenase (IMPDH), an enzyme that is critical for cells to be able to synthesize guanosine triphosphate (GTP), a molecule required for DNA synthesis and cellular signaling.
AVN944 is an orally bioavailable inhibitor of inosine monophosphate dehydrogenase 1 and 2 (IMPDH).
Inosine 5'-monophosphate (IMP) acts synergistically with MSG when tasted.
Fox Foundation, says a vaccine against a protein, a blood-pressure drug called isradipine, and a supplement, inosine, looked promising in clinical trials.
Fox Foundation for Parkinson's Research (MJFF) - researchers found that oral ingestion of the urate precursor inosine is safe and tolerable and raises levels of urate in the blood and in the cerebrospinal fluid bathing the brain.
The peaks of the individual nucleotides were identified using the retention times for standards: hypoxanthine, inosine, inosine-5'-monophosphate (IMP), adenosine-5'monophosphate (AMP) (Sigma, USA), and the concentration was calculated using the area for each peak.
Degenerate and Inosine nucleosides whose properties are otherwise hard to predict are also supported.
4) Raising uric acid levels can be beneficial in the treatment of MS and inosine supplementation is emerging as a method of achieving this goal.
Washington, Jan 26 (ANI): Scientists have discovered two functional variants in the inosine triphosphatase (ITPA) gene that protect patients with hepatitis C virus (HCV) against anemia brought on by antiviral treatment.
Adenosine deaminase (ADA) is an enzyme in the purine salvage pathway that catalyses the conversion of adenosine and deoxyadenosine to inosine and deoxyinosine with the release of ammonia.