indinavir


Also found in: Dictionary, Medical, Encyclopedia, Wikipedia.
Related to indinavir: nelfinavir, saquinavir
Graphic Thesaurus  🔍
Display ON
Animation ON
Legend
Synonym
Antonym
Related
  • noun

Synonyms for indinavir

a protease inhibitor (trade name Crixivan) used for treating HIV

Synonyms

References in periodicals archive ?
Then we used the GLUT-4 antagonist indinavir to exam the function of GLUT-4 and we observed that the uptake of 2-NBDG decreased when the indinavir was applied.
Ingrown toenail and indinavir: A case control study demonstrates strong relationship.
[12] Prominent effects are observed with Indinavir and ritonavir, diabetes began to appear when the drugs are in use in HIV-infected patients.
Indinavir and ritonavir are anti-HIV agents that selectively inhibit the HIV type 1 protease (9).
Patients with metabolic syndrome had significantly longer median (IQR) duration of indinavir exposure than patients without metabolic syndrome [42.8 (16.9-53.6) versus 0 (0-32.2) months; OR: 1.03, 95% CI: 1.0-1.06; p = 0.020].
Increased incidence of indinavir nephrolithiasis in patients with hepatitis B or C virus infection.
De estos compuestos el que tiene mayor afinidad por la proteina es el compuesto 18939759 que se encontraba en el grupo del Indinavir. En la figura 1 se muestra los sitios de interaccion del ligando con la proteina correspondientes a los residuos; Asn 301, Asp 86, Thr 222, Thr 221 (con dos interacciones), Tir 225 y Asn 131.
All pregnant ladies, first time stone formers and those patients taking antacid, indinavir or potassium sparing diuretics were excluded from the study.
In another report, three protease inhibitors indinavir (IDV), LPV, and RTV were determined simultaneously by UPLC-MS/MS [26].
"Old HAART" was defined as triple combination antiretroviral regimens containing indinavir, saquinavir, fosamprenavir, nelfinavir, or nevirapine.
For example, one study found that supplementation with 1000 mg per day of vitamin C decreased plasma indinavir concentrations in patients receiving indinavir as a component of HAART.
Indinavir, a protease inhibitor used in the treatment of HIV infection, is a well-documented cause of crystal-induced acute kidney injury and chronic kidney disease.
Because depression is common among patients with HIV, my colleagues and I evaluated the pharmacokinetic effects of indinavir on venlafaxine and venlafaxine on indinavir to determine if venlafaxine would be safe to use in a patient taking a PI because of potential cytochrome P450 (CYP450) drug interactions in both classes of medications.2 Adding ven-lafaxine resulted in a 36% decrease in maximum concentrations for indinavir and a 28% decrease in area under the curve (Figure).2 Study participants were healthy individuals; however, we concluded that had we studied patients with HIV, indinavir efficacy could decrease, resulting in an increased viral load.