Then we used the GLUT-4 antagonist indinavir
to exam the function of GLUT-4 and we observed that the uptake of 2-NBDG decreased when the indinavir
Ingrown toenail and indinavir
: A case control study demonstrates strong relationship.
 Prominent effects are observed with Indinavir
and ritonavir, diabetes began to appear when the drugs are in use in HIV-infected patients.
and ritonavir are anti-HIV agents that selectively inhibit the HIV type 1 protease (9).
Patients with metabolic syndrome had significantly longer median (IQR) duration of indinavir
exposure than patients without metabolic syndrome [42.8 (16.9-53.6) versus 0 (0-32.2) months; OR: 1.03, 95% CI: 1.0-1.06; p = 0.020].
Increased incidence of indinavir
nephrolithiasis in patients with hepatitis B or C virus infection.
De estos compuestos el que tiene mayor afinidad por la proteina es el compuesto 18939759 que se encontraba en el grupo del Indinavir
. En la figura 1 se muestra los sitios de interaccion del ligando con la proteina correspondientes a los residuos; Asn 301, Asp 86, Thr 222, Thr 221 (con dos interacciones), Tir 225 y Asn 131.
All pregnant ladies, first time stone formers and those patients taking antacid, indinavir
or potassium sparing diuretics were excluded from the study.
In another report, three protease inhibitors indinavir
(IDV), LPV, and RTV were determined simultaneously by UPLC-MS/MS .
"Old HAART" was defined as triple combination antiretroviral regimens containing indinavir
, saquinavir, fosamprenavir, nelfinavir, or nevirapine.
For example, one study found that supplementation with 1000 mg per day of vitamin C decreased plasma indinavir
concentrations in patients receiving indinavir
as a component of HAART.
, a protease inhibitor used in the treatment of HIV infection, is a well-documented cause of crystal-induced acute kidney injury and chronic kidney disease.
Because depression is common among patients with HIV, my colleagues and I evaluated the pharmacokinetic effects of indinavir
on venlafaxine and venlafaxine on indinavir
to determine if venlafaxine would be safe to use in a patient taking a PI because of potential cytochrome P450 (CYP450) drug interactions in both classes of medications.2 Adding ven-lafaxine resulted in a 36% decrease in maximum concentrations for indinavir
and a 28% decrease in area under the curve (Figure).2 Study participants were healthy individuals; however, we concluded that had we studied patients with HIV, indinavir
efficacy could decrease, resulting in an increased viral load.