leads to serious complications for the mother and fetus, including premature labor and high fetal mortality.
Screening for ACTH-dependent hypercortisolism
in patients affected with pituitary incidentaloma.
Specifically, mitotane was given before surgery to the five patients with Cushing's syndrome because of hypercortisolism
not amenable by other inhibitors of steroidogenesis; the remaining 3 patients were treated with mitotane as adjuvant therapy before second operation for recurrent disease.
Varenna, "Bone involvement in exogenous hypercortisolism
," Journal of Endocrinological Investigation, vol.
Patients with following conditions were excluded from the study: obstructive airways disease other than COPD (bronchiectasis, cystic fibrosis or fibrosis due to tuberculosis), smoking within the last one month, patients on steroids, known thyroid diseases, hypercortisolism
, diabetes mellitus, hyperlipidemias, ischemic heart disease, non-pulmonary infective diseases, renal, cardiac or hepatic failures, autoimmune diseases and malignancies.
Potential subjects were excluded if they had hypertension, coronary artery disease, congestive heart failure, systemic rheumatic disease, diabetes mellitus, thyroiditis, renal disease, hypercortisolism
, or hyperprolactinemia; had used oral contraceptives, other hormone treatments, or any kind of medicine in the previous 3 months; were pregnant or breastfeeding; active smokers; or chronic alcohol consumers.
The most common signs of hypercortisolism
are weight gain, short in stature, muscle weakness, altered mood, delayed sexual development, thin skin, acne, and acanthosis nigricans.
McCune-Albright Syndrome (MAS) is a considerably rare syndrome in which hyperthyroidism, hyperparathyroidism, hypercortisolism
, excessive secretion of growth hormone and prolactin may be observed in addition to the three classical findings (1, 2).
Neuroendocrine aspects of hypercortisolism
in major depression.
21] Both glucocorticoid use and endogenous hypercortisolism
(Cushing's disease) resulted in elevated TC and LDL cholesterol.
4] It is characterized by hypercortisolism
and side effects of excessive steroids are hyperglycemia, hypertension, fluid overload, protein catabolism, immune-suppression, increased susceptibility to infection and impaired wound healing.
Therefore, we diagnosed this patient with adrenal myelolipoma associated with hypercortisolism
and hypothyroidism in an infant with Smith-Lemli-Opitz syndrome.
Although several variables have been studied as a possible predictor for the efficacy of ECT but results regarding hypercortisolism
have been inconsistent.
3) Cushing's syndrome may prevent conception because the associated hypercortisolism
and hyperandrogenism affect normal follicular and endometrial development.