Several trials have compared the efficacy and side effects of intravenous bolus injections of hydralazine
to either IV labetalol or oral rapid-acting nifedipine as well as oral nifedipine to IV labetalol.
From the cohort of 80 subjects, patients started on hydralazine
plus nitrates formed one arm (n = 40) and those being managed without them but on conventional anti-failure therapy formed the other arm (n = 40).
Patient demographics, clinical features, dose and duration of hydralazine
exposure, and details of immunosuppressive therapy were abstracted retrospectively from the electronic medical records.
The diagnosis of DILE due to hydralazine
causing pericardial effusion was made.
Certain medications such as iron supplements, hydralazine
, hydrochlorothiazide, propranolol and furosemide have been associated with the condition.8,9 Although oral iron therapy seems to have the strongest association, pseudomelanosis has been described in its absence.
hydrochloride (1-hydrazinophthalazine hydrochloride) is a vasodilator and is used for the treatment of primary hypertension of moderate severity .
Current treatment is yet an evolving field, but standard of care is analogous to management of other types of HF (i.e., includes low-salt diet, fluid restriction, blood pressure control, loop diuretics, ACE-i or angiotensin receptor blocker therapy, beta blockade, nitrates, and hydralazine
Well-known drugs associated with AIH-like features include minocycline, alpha methyldopa, nitrofurantoin, diclofenac, hydralazine
, and antitumor necrosis factor-alfa antagonists.
was first introduced as an antihypertensive in 1951, with the first cases of HIL observed two years later in 1953 [1, 2].
Her prescribed home medications included omeprazole, divalproex, dicyclomine, and numerous antihypertensive medications including hydralazine
which was initiated approximately 18 months prior to this admission.
Calcein-AM bioreagent, trolox, diphenylene iodonium (DPI), GW4869, Vas2870, and hydralazine
were from Sigma, and 4-HNE was from Calbiochem, [methyl-[sup.14]C]choline-sphingomyelin was from Perkin-Elmer.
Objective: To compare oral nifedipine with intravenous hydralazine
in their rapidity to control hypertensive emergencies of pregnancy.
In the SA public sector, particularly at the primary healthcare level, the availability of hydralazine
launch of hydralazine
hydrochloride injection USP, 20 mg/mL, which is a generic version of Novartis AG's Apresoline Injection, 20 mg/mL.
Mylan, a global generic and specialty pharmaceuticals company registered in the Netherlands, has launched its Hydralazine
Hydrochloride Injection USP, 20 mg/mL in the United States it was reported on Friday.