homozygote


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  • noun

Words related to homozygote

(genetics) an organism having two identical alleles of a particular gene and so breeding true for the particular characteristic

References in periodicals archive ?
In the codominant model of mutational homozygote vs wild homozygote, significant results were found in 3 polymorphisms: rs2280091 (OR=4.
It would be particularly beneficial for animals with long gestation period to save the time required for breeding for the production of homozygote animals from the verified heterozygotes.
From the MTHFR gene mutations examined, while no mutation was found in C677T, homozygote mutation in A1298C was determined.
As for the GC polymorphisms, the GC2 homozygote (GC2/GC2) was found to be significantly associated with asthma (OR = 3.
A homozygote carrier of a Robertsonian translocation (13q;14q) was reported in this paper who was phenotypically normal.
Increased proportion of KIR3DS1 homozygotes in HIV-exposed uninfected individuals.
Regarding homozygote/heterozygote for RHCE, we observed following results: dominant homozygote CC-12.
In the second phase, we created two dummy variables for each SNP: heterozygote (major homozygote as referent) and homozygote variant (major homozygote as referent).
Several studies have demonstrated that approximately 80 to 100% of patients with the hemochromatosis phenotype are homozygote for the C282Y mutation (3-5).
They stated that none of the MTHFR homozygote had high homocysteine levels.
Because of the low frequency of the [alpha]-adducin Trp460Trp homozygote, patients with Gly460Trp and Trp460Trp genotypes were enrolled together to Group 2 (n=21) for further analysis.
Heterozygote EMs (CYP2C19*1/*2) and mutant homozygote PMs (CYP2C19*2/*2) demonstrate 52 and 11 per cent activity of OPZ hydroxylase compared to normal homozygote EMs (CYP2C19*1/*1), thus demonstrating a gene dose effect.
Therefore, a homozygote is usually very ill while a heterozygote is either asymptomatic (carrier) or exhibits mild symptoms.