In the codominant model of mutational homozygote
vs wild homozygote
, significant results were found in 3 polymorphisms: rs2280091 (OR=4.
It would be particularly beneficial for animals with long gestation period to save the time required for breeding for the production of homozygote
animals from the verified heterozygotes.
41 for PF, that is, there was an excess of 34% of homozygotes
in the PC sample and 41% in the PF sample.
From the MTHFR gene mutations examined, while no mutation was found in C677T, homozygote
mutation in A1298C was determined.
As for the GC polymorphisms, the GC2 homozygote
(GC2/GC2) was found to be significantly associated with asthma (OR = 3.
carrier of a Robertsonian translocation (13q;14q) was reported in this paper who was phenotypically normal.
Increased proportion of KIR3DS1 homozygotes
in HIV-exposed uninfected individuals.
/heterozygote for RHCE, we observed following results: dominant homozygote
In the second phase, we created two dummy variables for each SNP: heterozygote (major homozygote
as referent) and homozygote
variant (major homozygote
Several studies have demonstrated that approximately 80 to 100% of patients with the hemochromatosis phenotype are homozygote
for the C282Y mutation (3-5).
They stated that none of the MTHFR homozygote
had high homocysteine levels.
Because of the low frequency of the [alpha]-adducin Trp460Trp homozygote
, patients with Gly460Trp and Trp460Trp genotypes were enrolled together to Group 2 (n=21) for further analysis.
Heterozygote EMs (CYP2C19*1/*2) and mutant homozygote
PMs (CYP2C19*2/*2) demonstrate 52 and 11 per cent activity of OPZ hydroxylase compared to normal homozygote
EMs (CYP2C19*1/*1), thus demonstrating a gene dose effect.
mutated genotype (nn) was not cut by the restriction enzyme, and the heterozygote (Nn) produced three fragments of 144, 95 and 49bp, respectively.
Therefore, a homozygote
is usually very ill while a heterozygote is either asymptomatic (carrier) or exhibits mild symptoms.