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  • noun

Words related to homozygote

(genetics) an organism having two identical alleles of a particular gene and so breeding true for the particular characteristic

References in periodicals archive ?
First, other HFE genotypes, including the compound heterozygote encoding the Cys282Tyr and His63Asp mutations, have been associated with an HH phenotype, although individuals with such genotypes accumulate less iron than Cys282Tyr homozygotes (1-3).
After enrichment for rare F5 [coagulation factor V (proaccelerin, labile factor)] homozygotes, [6] F2 [coagulation factor II (thrombin)] heterozygotes, and F2 homozygotes, DNA was extracted (Gentra Puregene Blood Kit, Qiagen) and diluted to 200 ng/[micro]L with 10mmol/LTris, pH 8.
In previous studies, the percentage of homozygote of this mutation has reached to 5.
Compared with the MT1M (rs2270836) homozygote genotype GG, subjects with homozygote variant genotype AA had lower urinary mercury levels [Table 4; sec Supplemental Material, Figure la, b (http://dx.
Patients were classified according to their [alpha]-adducin gene polymorphisms; Gly460Gly homozygotes--Group 1 (n=28) and Trp460Trp homozygotes and Gly460Trp heterozygotes--Group 2 (n=21).
In contrast, normal homozygote EMs (CYP2C19*1/*1 ) have both the normal alleles and heterozygote EMs have one normal allele that leads to the synthesis of active CYP2C19 enzyme leading to efficient metabolism of OPZ to 5-OH-OPZ.
Polymorphism in intron 4 of HFE may cause overestimation of C282Y homozygote prevalence in haemochromatosis [letter].
x is allele code substituted minor homozygote, heterozygote and major homozygote with 0, 1 and 2, respectively,
In this case, A1AT was not detectable and a Z/Z homozygote phenotype was found.
The homozygote and heterozygote groups were unified and a new group, namely, composed of those with the polymorphism was created.
However, the frequency of homozygote M694V mutations was higher in the colchicine-resistant group than the colchicine-responsive group (n=9, 33% versus n=11, 18.
However, because there were small sample sizes in HFE homozygote genotype, we were unable to test alleles dose responses.
It was found that SNPs in exon 6 constitute a haplotype and that QT dispersion and corrected QT dispersion in the rare homozygote (707C/710T/761C) type carriers of HCMP patients for this haplotype were significantly lower than other genotypes (p=0.