hepatotoxic

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Words related to hepatotoxic

toxic to the liver

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References in periodicals archive ?
The mean age of individuals for which an herbal/ dietary supplement was thought to be the cause of the hepatotoxicity was 36.
Approaches for predicting hepatotoxicity in silico have been proposed based on chemical structure similarity through the development of quantitative structure-activity relationship (QSAR) models (Chen et al.
Hepatotoxicity attacks were defined as impairment in liver function tests that was responsive to drug dose reduction or discontinuation, or treatment of specific causes such as infectious complications.
6 Corrosion releases the metallic metabolites into the parenteral circulation which causes acute hepatotoxicity.
6,10) There is a lack of information from the region on the extent of ART related hepatotoxicity associated with or without hepatitis C virus.
Overall, 26 out of the 83 (24%) patients subsequently discontinued ABC treatment due to the following reasons: virologic failure (n=11), rash (n = 5), in three cases before the availability of genetic testing for HLA B*5701, gastrointestinal side effects (n = 2), pregnancy (n = 2), patient request (n = 2), one patient discontinued due to change in treatment strategy, one patient due to high cardiovascular risk, and hepatotoxicity (n = 2, both cases tested negative for HLA B*5701).
Acetaminophen (APAP), a widely used antipyretic and analgesic, can cause severe hepatotoxicity and liver failure when taken overdose.
The potential of a drug to cause hepatotoxicity is often realized after release onto the market [2] and it has been estimated that more than a thousand drugs have been associated with liver injury and hepatotoxicity [4, 5].
We report a case of clinically significant hepatotoxicity after a very brief course of rosuvastatin in a statin-naive patient.
Herbals and herbal nutritional products hepatotoxicity
8,9) The consistent and well-defined nature of acetaminophen-induced hepatotoxicity allowed for the introduction in 1977 of N-acetyl-cysteine as specific treatment for its toxicity.
Hepatologists and other specialists from around the world present 28 chapters on imaging, lab tests, fibrosis and fibrogenesis, pathophysiology, prognosis, and liver transplant evaluation, followed by the management of complications like hepatic encephalopathy, cirrhotic cardiomyopathy, hepatopulmonary syndrome, ascites, acute kidney injury, and hyponatremia, as well as bleeding, malnutrition, adrenal insufficiency, coagulopathy, infections, osteopenia, and pruritis, and pediatric considerations, drug therapy and potential hepatotoxicity, and quality of life.
Drug-induced hepatotoxicity accounts for approximately 50% of acute liver failure cases, and almost 10% of liver transplants in some facilities.