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Words related to hepatotoxic

toxic to the liver

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References in periodicals archive ?
Several PAs have been found to cause hepatotoxic, mutagenic and cancerogenic effects--accounting for the toxicological relevance of PAs to humans (Chen et al.
Silymarin, the active principle of the milk thistle Silybum marianum, protects experimental animals against various hepatotoxic substances.
21] Risk factors associated with severe ART-related hepatotoxicity were a baseline elevation in serum aminotransferases, concomitant hepatotoxic medication, thrombocytopenia, renal insufficiency, chronic HBV or HVC co-infection and female gender.
Wg toxicity is attributed to the presence of a hepatotoxic terpenoid called atractyloside, a powerful inhibitor of cellular respiration and ATP synthesis (7).
General anesthesia would be potentially hepatotoxic for our cirrhotic patient while the minimum of three entry points would be dangerous due to coagulation disorders.
However it should be noted that this advantage is tempered by continued concern regarding the hepatotoxic potential of kava preparations (potentially containing flavokawain B) derived from an ethanol extraction of ground Piper methysticum root (Kinrys 2009, Zhou 2010).
In addition, the study shows dendritic cell expansion successfully diminished the hepatotoxic effects of acetaminophen protecting the liver from damage.
A well-characterized example is the accumulation of a hepatotoxic intermediate in acetaminophen metabolism when the hepatic reserve of glutathione, which detoxifies the intermediate, is depleted by excess drug.
Moreover, recent controversy about the hepatoprotective versus hepatotoxic effects of Chelidonium majus has renewed the interest of the medical community in this plant.
Most of the hepatotoxic chemicals damage liver cells by inducing lipid peroxidation and other oxidative damages in liver (2-5)
Evidence indicates that the peeled kava rhizome should be used, but in some instances the aerial parts (which may contain the hepatotoxic alkaloid pipermethysticin) have been used.
To minimize hepatotoxic risks due to kava use, efforts have to be undertaken to improve kava qualify standards and to establish strict regulations for kava cultivators, farmers, harvesters, manufacturers and physicians hearing patients for anxiety, tension and restlessness," Dr.
Animal experirnents on the hepatotoxic effect of rnycotoxins.
Anti-TB chemotherapy containing isoniazid (H), rifampicin (R) and pyrazinamide (Z) has proved to be highly effective but hepatotoxic.