They found the pigment to be a hemoprotein
and named it cytochrome P450 (P450), i.
Eighteen studies (35%) employed a colorimetric method, which usually involved a preseparation step by centrifugation or filtration to remove hemoglobin, followed by a commercial dipstick for hemoprotein
(11, 14, 17, 26, 27, 29, 33-35, 38, 42, 45, 48, 52-54, 56, 57), and 19 (37%) used immunometric methods (11, 13, 18,19, 23, 28, 31, 32, 38, 43, 44, 46, 47, 51, 58-62).
The heme, which consists of a ring of carbons and nitrogens, is the portion of hemoprotein
that clasps the protein's iron atom in place.
One of them is myeloperoxidase (MPO), an abundant hemoprotein
of neutrophils, which is typically perceived to primarily mediate host defense reactions [5-7].
1968) Role of hemoprotein
P-450 in fatty acid [omega]-hydroxylation in a soluble enzyme system from liver microsomes.
The carbon monoxide binding pigment of liver microsomes, I: Evidence for its hemoprotein
1979) Electrical conduction of hemoprotein
in the solid phase: anhydrous cytochrome [c.
It is well known (White and Marletta 1992) that iNOS is a hemoprotein
that contains both a reductase and a heme domain on the same polypeptide.
Myeloperoxidase is a hemoprotein
(molecular mass of 140 kDa) consisting of a pair of heavy and light chains.
We hypothesized that after PM exposure, events linked to inflammation, such as hemoprotein
deposition and oxidative stress, should be present at the microvascular level.
CO production in mammals is at least 85% attributable to the HO-mediated degradation of hemoprotein
heme (58, 59).
Thyroperoxidase is a glycosylated hemoprotein
encoded by the TPO gene located on chromosome 2p25.
Myoglobin is a 17-kDa single-chain hemoprotein
found in skeletal and cardiac muscle.
ALA is a key precursor in the biosynthesis of heme, which is a prosthetic group of hemoproteins
, including cytoglobins, cytochrome, POD, SOD, and catalase (CAT) (HOODA et al.
Cytochrome P450 is a large family of hemoproteins
that catalyze the metabolism of a large number of xenobiotics and endobiotics (5).