We could assess the differences in CYFRA 21-1 values among hematuric and nonhematuric urine voided samples in a group of five patients who had intermittent periods of hematuria during the study (data not shown).
Because of the small differences found in those patients with intermittent periods of hematuria, we considered both samples, hematuric or nonhematuric, acceptable for the determination of CYFRA 21-1.