AHR antagonism is a clinically validated mechanism for expanding hematopoietic
stem cells, as we have reported in Phase 2 studies with the company's MGTA-456 cell therapy that uses the same mechanism.
CD117 is expressed on human hematopoietic
stem and progenitor cells and on leukemia cells in 80% of patients with acute myeloid leukemia and in 65% of patients with myelodysplastic syndromes ; CD45 is expressed on all lympho-hematopoietic cells and in nearly all blood cancers, other than multiple myeloma.
One elder brother's hematopoietic
stem cells showed only a half match.
The hPSCs/OP9 coculture system is a widely used approach to generate [CD34.sup.+] hematopoietic
cells from hPSCs without additional cytokine (9,12,13).
He was the first foreigner to use Chinese cord blood hematopoietic
"In conclusion, at 54 months after randomization, myeloablative CD34-positive selected autologous hematopoietic
stem-cell transplantation resulted in significantly better clinical outcomes than 12 months of cyclophosphamide," the researchers wrote.
Bone Marrow Mesenchymal Stem Cells and the Hematopoietic
[U.S.A], December 28 (ANI): In a new research, a group of scientists have managed to find the pernicious effect of obesity on the long-term health of blood-making stem cells (hematopoietic
They frequently contain mature adipose tissue and hematopoietic
elements (both myeloid and erythroid) (2).
stem cell transplantation is frequently used for treatment of many malign and benign diseases, particularly aplastic anaemia and thalassemia.
stem cell transplantation (HSCT) is an important treatment option for children with severe and refractory disease and debilitating clinical complications [3-5].
Thirty-six patients with hematologic cancers who were receiving high-dose chemotherapy and radiation therapy followed by hematopoietic
stem cell transplantation were treated (apparently without randomization) with zinc-L-carnosine in sodium alginate suspension (active treatment) or azulene gargles (control).
2011), it remains critical to identify the long-term cellular and molecular targets in the hematopoietic
Global Markets Direct's, 'Hematopoietic
Stem Cell Transplantation - Pipeline Review, H1 2016', provides an overview of the Hematopoietic
Stem Cell Transplantation pipeline landscape.
Cell Transplantation: Stem Cell Transplantation, 5th Edition; 2 volume set (online access included)