is 5 times more potent at blocking the muscarinic receptor than atropine.
, a long-acting muscarinic antagonist, is available as monotherapy.
is the preferred systemic medication for off-label hyperhidrosis treatment, and patients typically start at 1 mg twice daily, increasing the dose by 1 mg a day each week until they achieve the desired improvement or are unable to tolerate adverse effects, he said.
Trzcinski, "Use of glycopyrrolate
and other anticholinergic medications for sialorrhea in children with cerebral palsy," Clinical Pediatrics, vol.
I actually prefer glycopyrrolate
, because it does not cross the bloodbrain barrier, so it is associated with fewer overall systemic and neurologic side effects," Dr.
5 mg and glycopyrrolate
500 [micro]g) was administered and recovery was uneventful.
Neostigmine and glycopyrrolate
were used to reverse muscle paralysis and the patient was extubated.
The three most commonly used anticholinergic medications to treat the death rattle in the dying patient are hyoscine hydrobromide (Scopolamine[R]), hyoscyamine sulfate (Levsin[R]), and glycopyrrolate
(Robinul[R]) (see Table 2).
is a quaternary ammonium compound used perioperatively to reduce salivary and respiratory secretions.
If it is severe and affects the scalp as well, medication can help, such as the anticholinergic drug called glycopyrrolate
For a patient who is conscious, a better alternative anticholinergic agent is intravenous glycopyrrolate
Comparison of IV glycopyrrolate
and atropine in the prevention of bradycardia and arrythmias following repeated doses of suxamethonium in children.
The agents--available under numerous trade names--include atropine, belladonna, dicyclomine, glycopyrrolate
, L-hyoscyamine, mepenzo-late, methscopolamine, propantheline, and scopolamine.
is commonly used to decrease copious secretions and to prevent traction-induced vagal inhibitory cardiac reflexes.