[USPRwire, Wed Aug 21 2019] Factor XIII
deficiency is a rare genetic blood disorder that is characterised by the deficiency of clotting factor XIII
[ClickPress, Thu Jul 25 2019] The significant presence of communities that follow consanguineous marriages increases the risk of passing on factor XIII
deficiency to the next generations, which is driving the factor XIII
deficiency treatment market.
Val34Leu variant protects against coronary artery disease.
Burch, "The impact of factor XIII
on coagulation kinetics and clot strength determined by thrombelastography," Anesthesia & Analgesia, vol.
As factor XIII
has a long half-life, prophylactic replacement therapy every 4 weeks with factor XIII
concentrate or cryoprecipitate is effective as a preventive strategy.
Role of factor XIII
in fibrin clot formation and effects of genetic polymorphisms.
(7,15) Besides this, SGH can be the first manifestation of underlying coagulopathy such as von Willebrand disease and factor XIII
Objective: To provide a comprehensive literature review on roles of coagulation factor XIII
(FXIII) in coagulation, wound healing, neoplasm, bone metabolism, and pregnancy.
Coagulation factor XIII
(FXIII) is activated by thrombin into activated FXIII (FXIIIa).
Hoppe, "Fibrinogen and factor XIII
at the intersection of coagulation, fibrinolysis and inflammation," Thrombosis and Haemostasis, vol.
Determinacion de Factor XIII
(Factor Estabilizador de la fibrina).
It converts fibrinogen to fibrin and activates factor XIII
, platelets, and smooth muscle constriction (Biologies 2008;2:593-9).
(FXIII) deficiency is a rare (autosomal recessive) genetic disorder which is associated with delayed bleeding symptoms that occur hour or days after trauma.
(FXIII) is one of the main contributors to clot formation in the final stages of coagulation.
Although AHA is thus clinically and economically an important disorder, it is often unrecognized or misdiagnosed as other acquired hemorrhagic disorders, such as disseminated intravascular coagulation (DIC) and acquired inhibitors against von Willebrand factor (acquired von Willebrand syndrome ) and factor XIII
(acquired factor XIII