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Related to estrange: disaffect, regress
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  • verb

Synonyms for estrange

to make distant, hostile, or unsympathetic

Synonyms for estrange

remove from customary environment or associations

arouse hostility or indifference in where there had formerly been love, affection, or friendliness

References in classic literature ?
He deemed it best not to put his parents into communication with her by informing them of her address; and, being unaware of what had really happened to estrange the two, neither his father nor his mother suggested that he should do so.
If there'd been a divorce between mum and dad, the young person may decide they can't be friends with both, so estranges one.