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Related to endoneurium: perineurium
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  • noun

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delicate connective tissue around individual nerve fibers in nerve

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(6) Seddon Sunderland Structural and functional processes Neurapraxia 1 Myelin damage, conduction slowing, and blocking Axonotmesis 2 Loss of axonal continuity; endoneurium intact; no conduction Neurotmesis 3 Loss of axonal and endoneurial continuity; perineurium intact; no conduction 4 Loss of axonal, endoneurial, and perineurial continuity; epineurium intact; no conduction 5 Entire nerve trunk separated; no conduction
Caption: Figure 2: (a) Dilated venule (arrow) within the endoneurium of sciatic nerve with aggregated blood cells and their penetration (diapedesis) through the vessel wall (arrowhead).
In the present study, it should be noted that (in the histological studies) the epineurium was never disrupted in any of the groups, but the perineurium and endoneurium were affected.
(1) Histologically, each peripheral nerve consists of axons, Schwann cells that form myelin sheaths around some axons, endoneurium, perineurium, and epineurium.
(5) The deposits are located in the endoneurium and within blood vessel walls.
In histology analysis, the features shown on the slide collection were observed and described, as the following structures: epineurium, perineurium and endoneurium, nerve fiber, inflammatory infiltrate, Schwann cells, fibroblasts, and blood vessels.
Electron microscopic evaluation of the resected specimens of interdigital neuroma reported edema of the endoneurium, fibrosis beneath the perineurium, axonal degeneration, and necrosis, which suggested nerve damage secondary to mechanical impingement by adjacent structures [27].
Amyloid deposits were present in the perineurium, endoneurium, and endoneurial arterioles in two patients (1 and 4), and only in a single endoneurial arterioles in one patient (2).
(3) The individual axons of the nerve are surrounded by the endoneurium and subsequently bound together in fascicles by the perineurium.
The large peripheral nerves are composed of Schwann cell-axon complexes, supported and protected by 3 connective-tissue sheaths: endoneurium, perineurium, and epineurium.
The facial nerve, alike all peripheral nerves, has free nerve endings in the perineurium and endoneurium, derived from fibres in the nerve trunk itself, which have nociceptive function [19].
Myelinated and unmyelinated nerve fibers are grouped together in bundles called fascicles, dispersed in a loose connective tissue called endoneurium, and then enclosed in a membrane of flattened cells called perineurium.
Sixteen sciatic nerve transverse cuts and 8 transverse cuts of the thoracic portion of the sympathetic trunk were used, processed according to the classical histological technique, taking into account the diameter of the nerve fibers, endoneurium characteristics, number and shape of Schwann cells, using an image analyzer software.
All nerve biopsies displayed inflammatory cell infiltrate with vacuolated cells, fibrosis of the perineurium, endoneurium and endoneural vessels (Figure 1, Table 3).