diazoxide


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Synonyms for diazoxide

vasodilator (trade name Hyperstat) used to treat severe hypertension

References in periodicals archive ?
Diazoxide choline has received Orphan Drug Designation for the treatment of PWS in the U.S.
We report a new case with an adverse event of diazoxide. This patient, a 15-month-old girl with Kabuki syndrome (KS), developed a severe pericardial effusion following diazoxide.
The parent molecule, diazoxide, has been used for decades in thousands of patients in a few rare diseases in neonates, infants, children and adults, but has not been approved for use in PWS.
All patients were treated with diazoxide, with doses ranging from 2 to 12.5 mg/kg/d.
Two patients with benign insulinomas were inoperable due to other diseases: one of them was treated with diazoxide, and the symptoms did not progress during the 6-year follow-up.
Jahangir, "Cardiac Subsarcolemmal and Interfibrillar Mitochondria Display Distinct Responsiveness to Protection by Diazoxide," Journal of PLOS ONE, vol.
Included patients with known diabetes, chronic renal failure, liver cell diseases, endocrine disorders such as insulinoma, postpancreatectomy, patients on drugs such as somatostatin, beta blockers, diazoxide, thiazide diuretics, phenytoin, alloxan, and steroids pregnant women, post-menopausal women, people with fever, people who had edema, patient with osteoporosis with very low bone density, body builders or professional athletes, patients undergoing dialysis, and persons with pacemaker were excluded from the study.
With suspicious diagnosis of hyperinsulinism, treatment with diazoxide was started and, according to unusual age of the presentation, spiral abdominal CT scan with intravenous and oral contrast was done.
Participants showed no evidence of skin disorders, had no history of cardiovascular, renal, or hepatic disease, and did not admit to applying any topical treatment drug (steroids, cytotoxic agents, vasodilators, antihypertensives, anticonvulsants, [beta]-blockers, and diuretics) or any of the following agents: spironolactone, cimetidine, diazoxide, cyclosporine, ketoconazole, or replacement hormones.
Upregulation of UQCRC1 by Diazoxide. To measure the mitochondrial free [Zn.sup.2+] concentration in cells that overexpressed UQCRC1 or cells in which UQCRC1 was downregulated, H9c2 cells were stained with RhodZin-3, a [Zn.sup.2+]-selective fluorescence dye that targets mitochondria.
The combined company will be well-positioned to advance diazoxide choline controlled release tablet, a once-daily oral tablet for the treatment of patients with Prader-Willi syndrome.
Diazoxide in the management of patients with insulinoma.
Age-and gender-related differences in mitochondrial oxygen consumption and calcium with cardioplegia and diazoxide. Ann Thorac Surg.
Exclusion criteria included conditions that affect the production of SHBG, including: cirrhosis of the liver; gonadal abnormalities; and medications such as phenytoin, androgens, growth hormone, high-dose glucocorticoids, diazoxide, epinephrine, cortisol, progestin, and sulfonylureas.
In distinction, the stimulatory effect was inhibited with diazoxide, nifedipine, EGTA and K+ depolarized media.