When the desensitization procedure is conducted in the actual presence of the feared object or situation, the desensitization is said to be conducted "in vivo," or "in life," as opposed to being conducted via one's imagination or through photographs, etc.
Robert Moore, PhD, describes this process as "?TIR is a regressive desensitization procedure for reducing or eliminating the negative residual impact of traumatic experience." It is a one-on-one guided imagery process.
HSR is thought to be a Type I hypersensitivity Ig-Emediated reaction as the patients develops HSR after multiple infusions of oxaliplatin. Readministering oxaliplatin to patients with HSRs has been attempted using several methods, such as using prophylactic agents (i.e., hydrocortisone and antihistamines), extending administration time, and using desensitization procedures.
Interestingly, the authors attributed the changes in his behavior not to the desensitization procedures but to the information he obtained during treatment--probably the first time he'd ever had straight answers to his questions (Klepac, Lander & Godding, 1984).