delavirdine


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Synonyms for delavirdine

a non-nucleoside reverse transcriptase inhibitor (trade name Rescriptor) used to treat AIDS and HIV

References in periodicals archive ?
Transport of stavudine, delavirdine, and saquinavir across the blood-brain barrier by polybutylcyanoacrylate, methylmethacrylate-sulfopropylmethacrylate, and solid lipid nanoparticles.
Common medications that are pH dependent for absorption are the azole antifungals, ampicillin, cefpodoxime, indinavir, delavirdine, cyanocobalamin, iron, and digoxin.
The parent study was a randomized, double-blind clinical trial of delavirdine mesylate, which is in a nonnucleoside reverse transcriptase inhibitor (NNRTI) of HIV (Weinfurt et al.
Table 1 Common Antiretroviral Drugs (14-16) Classification Generic Name Trade Name Nucleoside reverse Abacavir sulfate Ziagen transcriptase inhibitors Abacavir sulfate + Trizivir (NRTI) lamivudine + zidovudine Didanosine (ddl) Videx, Videx EC Lamivudine (3TC) Epivir Lamiudine + zidovudine Combivir Stavudine (d4T) Zerit Tenofovir disoproxil Viread fumarate Zalcitabine (ddC) Hivid Zidovudine (AZT, ZDV) Retrovir Non-nucleoside reverse Delavirdine mesylate Rescriptor transcriptase inhibitors Efavirenz Sustiva (NNRTI) Nevirapine Viramune Protease inhibitors (PI) Amprenavir Agenerase Indinavir sulfate Crixivan Lopinavir + ritonavir Kaletra Nelfinavir Viracept Ritonavir Norvir Saquinavir Fortovase Saquinavir mesylate Invirase Fusion inhibitors (FI) Enfuvirtide Fuzeon
Patients whose background treatment regimen included a protease inhibitor or delavirdine received the lower dose.
This category includes nevirapine, efavirnz, and delavirdine. A common side effect is a skin rash that may be mild, uneventful and resolve in a few days or be serious and potentially life-threatening.
(34) There are three FDA approved NNRTIs: nevirapine, delavirdine, and efavirenz.
Delavirdine, Efaverenz, and Nevirapine are commonly used from this very specific drug class.
Currently, three groups of drugs are available for the treatment of the HIV infection: the nucleoside inhibitors of reverse transcriptase (zidovudine, didanosine, lamivudine, stavudine, abacavir, zalcitabine), the non-nucleoside inhibitors of reverse transcriptase (nevirapine, delavirdine, efavirenz), and the protease inhibitors (indinavir, nelfinavir, ritonavir, saquinavir, amprenavir, lopinavir).
* Delavirdine mesylate inhibits cytochrome P-450, leading to a significant increase in methadone concentrations--the half-life is extended by almost 50%.
The K103N mutation causes high-level resistance to nevirapine as well as cross-resistance to other nonnucleoside reverse transcriptase inhibitors, including efavirenz and delavirdine, he said at a conference on retroviruses and opportunistic infections.
En la Grafica 2a y b se presentan las principales mutaciones que cambian codones de la secuencia de aminoacidos de la RT salvaje y que exhiben resistencia a los NRTI (zidovudine, didanosine, zalcitibine, stavudine, lamivudine, y abacavir) y a los NNRTI (nevirapine, delavirdine y enfavirenz).
Currently available anti-HIV drugs Protease Inhibitors Nucleotide Reverse Agenerase (generic name: amprenavir) Transcriptase Inhibitor Crixivan (indinavir) Viread (tenofovir, PMPA) Fortovase (saquinavir) Kaletra (lopinavir plus ritonavir) Nucleoside Reverse Norvir (ritonavir) Transcriptase Inhibitors Viracept (nelfinavir) Combivir (AZT plus 3TC) Epivir (lamivudine, also Nonnucleoside Reverse known as 3TC) Transcriptase Inhibitors Hivid (zalcitabine, ddC) Rescriptor (delavirdine) Retrovir (zidovudine, AZT) Sustiva (efavirenz) Trizivir (abacavir plus AZT plus 3TC) Viramune (nevirapine) Videx (didanosine, ddl) Zerit (stavudine, d4T) Ziagen (abacavir)
Researchers in Denmark report that the protease inhibitor amprenavir (Agenerase) lowers the levels of delavirdine (Rescriptor).