On analysing for correlation and associations, it was found that patients of cirrhosis having ECG abnormalities (QTc interval prolongation), increased systolic dysfunction, increased diastolic dysfunction, decreased cardiac output
, decreased cardiac index and increase in proBNP levels were significantly associated (p value <0.
Decreased cardiac output
may cause an S3 and/or S4 on auscultation of heart sounds, but blood pressure is a more immediately relevant assessment.
In conditions with a fixed ventricular outflow obstruction it is not only the decreased cardiac output
that plays a role, but also a reflex vasodilation or orthostatic hypotension.
The decreased cardiac output
stimulates sympathetic activity and blood volume expansion via the activation of the reninangiotensin-aldosterone axis.
It's likely that anergia is related to the decreased cardiac output
and low blood pressure often found in heart failure.
A patient who is hypovolemic, or a patient who has decreased cardiac output
from an MI, will exhibit a decrease in the systolic pressure.
However, in fulminant cases, impaired venous return and decreased cardiac output
might result in potentially fatal hypotension.