Comparison of the cytotoxicity in vitro of temozolomide and dacarbazine
, prodrugs of 3-methyl-(triazen-1-yl) imidazole-4-carboxamide.
The 3-year OS rate was 51.2% in the nivolumab group, compared with 21.6% in the dacarbazine
group, an approximate 130% difference.
Kefford, "Phase 3, randomized, open-label, multicenter trial of nabpaclitaxel (nab-P) vs dacarbazine
(DTIC) in previously untreated patients with metastatic malignant melanoma (MMM)," Pigment Cell & Melanoma Research, vol.
Finally, chemotherapy was prescribed as follows: fotemustine alone for patient 3, dacarbazine
combined with fotemustine for patient 6, or carboplatin for patients 9 and 10, and achieved, respectively, 1 PD, 1 CR, 1 PD, and 1 SD.
For example, dacarbazine
resulted in a low response rate (10-15%) and an overall survival (OS) of eight months.
However, left cervical lymph node metastasis was found on MRI within 1 month after the treatment; therefore, she underwent additional proton-beam radiotherapy of her neck and immune-chemotherapy consisting of dacarbazine
, nimustine, vincristine, and interferon Two months later, CT examination revealed metastatic lesions in the liver and sternum.
All patients received ABVD (Adriamycin, Bleomycin, Vinblastine and Dacarbazine
) chemotherapy regimen except 2: One of them received VEPEMB regimen and other patient received ChlVPP chemotherapy.
Study 309 was a Phase III clinical study which examined the efficacy and safety of eribulin versus dacarbazine
in 452 patients aged 18 years and older with locally advanced, recurrent or metastatic soft tissue sarcoma (liposarcoma or leiomyosarcoma) who had disease progression following standard therapies (including an anthracycline and at least one other additional regimen).(1)
The present study was designed to investigate the anticancer potential of saponin extracted from sea cucumber Holothuria teucospiiata alone and in combination with dacarbazine
on B16F10 melanoma cell line.
Therefore, the present study aims to find out histological changes induced by the treatment of one of the drugs used in cancer chemotherapy, Dacarbazine
, on testicular tissue and the effectiveness of propolis in the reduction of these changes.
This trial was limited to BRAF V600-mutated melanomas and demonstrated a significant improvement in overall survival at 6 months in patients treated with vemurafenib as compared to dacarbazine
, the only chemotherapeutic agent approved for treatment of metastatic melanoma at the time.
The editor has organized the contributions that make up the main body of the text in three alphabetical volumes devoted to abarelix, barium enema, cancer biology, dacarbazine
, endocrine system tumors, xerostomia, zolpidem, and a wide variety of other related subjects in between.
, commonly used to treat skin cancer, was blended into the solution prior to crosslinking (a final part of the 3D printing process).
The focused light pattern delivered through several optics is projected and crosslinks a photopolymer." Dacarbazine
, commonly used to treat skin cancer, was blended into the solution before crosslinking.
The Oncological Board re-evaluated the case and decided, according to patient's options, refraining from secondary surgical intervention and starting adjuvant chemotherapy with Dacarbazine