Invasive cribriform carcinoma
ina Chinese population: comparison with low-grade invasive ductal carcinoma-not otherwise specified.
Eight of 10 patients showed invasive carcinomas (5 cases of ductal invasive (NST) carcinoma, two cases of mixed type invasive carcinoma (one case of invasive cribriform, tubular and NST carcinoma, and one case of micropapillary and NST carcinoma), one very rare case of bilateral synchronous invasive cribriform carcinoma
(Figure 1), and one case of extremely rare histologic type--adenomyoepithelioma of the male breast (with malignant behavior) (Table 1).
Andea, "Primary cutaneous cribriform carcinoma
: report of six cases with clinicopathologic data and immunohistochemical profile," Journal of Cutaneous Pathology, vol.
of the prostate and cribriform prostatic intraepithelial neoplasia: incidence and clinical implications.
Low grade ductal carcinoma in-situ, some tubular carcinoma and cribriform carcinoma
my yield deceptively 'benign' aspirates.
Among the 61 patients with malignant breast lesions, 53(86%) were diagnosed with invasive ductal carcinoma, 5(8%) invasive lobular carcinoma, 1(2%) patient each for medullary, metaplastic carcinoma and invasive cribriform carcinoma
. The range of tumour size in malignant breast cases was recorded (Figure-1).
Cribriform architecture characterizes several benign and malignant breast lesions, such as collagenous spherulosis, cribriform-pattern DCIS, invasive cribriform carcinoma
, and adenoid cystic carcinoma.
Occasionally, DCIS lesions need to also be distinguished from invasive carcinomas; a frequent such mimicker is invasive cribriform carcinoma
that needs to be distinguished mostly from cribriform DCIS.
Prostate lesions with cribriform or solid architectures range from benign and proliferative, such as central zone glands, clear cell cribriform hyperplasia, and basal cell hyperplasia, to invasive cribriform carcinoma
. Infrequently, cribriform or solid lesions comprise cytologically malignant cells spanning or filling glandular lumens and yet preserve, at least focally, a basal cell lining.