Human infections with OPVs frequently emerge or reemerge, including cowpox
virus in Europe (4), monkey-pox virus in Africa and North America (5), buffalopox in India (6), and VACV in South America (7), especially in Brazil (8).
Jenner infected an eight-year-old boy called James Phipps, his gardener's son, with cowpox
vaccine made mandatory in England (children)
Dr Robert Smith from Public Health Wales said: "Cowpox
is rarely reported these days either in animals, or more rarely, in humans.
was more common in the 18th century, when milking maids often caught it.
The one on his ankle was worrying - it was weeping a clear liquid down his ankle." After seeing their GP, they were sent straight to the Countess of Chester Hospital, where he was diagnosed with cowpox
Nearly 50 bulls and buffaloes have died from cowpox
while 100 others have the disease in Prek Meas and Thmor Key communes in Siam district, Steng Treng province, according to local authorities.
Jenner used fluid from a cowpox
blister, which he scratched onto the skin of a young boy; the boy was later shown to be immune to the far more deadly smallpox.
In the late 1700s and early 1800s, British physician Benjamin Jesty was using cowpox
virus to vaccinate people instead of the actual smallpox virus.
The book then follows the journey of a French medical doctor Jean Marie Despiau who was dispatched by the Nguyen royal court to Macao in 1820 to procure and preserve smallpox vaccine which used the less dangerous cowpox
virus for the vaccination of the royal children (chapter 2).
Differential diagnoses include, depending on the phase of the disease, anthrax, atypical mycobacteriosis, cowpox
, pseudocowpox (Milker's nodule), pyoderma, herpetic whitlow, tularemia, keratoacanthoma, fish-tank granuloma, and sporotrichosis [1, 2, 8].
It was an Englishman by the name of Edward Jenner who experimented in 1796 and injected cowpox
from a pustule on the arm of a milkmaid into a healthy boy named James Phipps.
'The story of vaccines did not begin with the first vaccine - Edward Jenner's use of material from cowpox
pustules to provide protection against smallpox.
The reason for this was that, as a child, living on a farm, she had had cowpox
. Mr C Beavor, Hall Green