releasing factor type-1 receptor antagonism in the dorsolateral bed nucleus of the stria terminalis disrupts contextually conditioned fear, but not unconditioned fear to a predator odor," Psychoneuroendocrinology, vol.
Pharmaceutical company ANI Pharmaceuticals Inc (NasdaqGM:ANIP) revealed on Tuesday the election of Karen Quinn PhD as vice president of its Corticotropin
Regulatory Affairs with immediate effect.
Orth, "Rapid radioimmunoassay for corticotropin
in unextracted human plasma," Clinical Chemistry, vol.
Medications were started during inpatient hospitalization in two-thirds of patients, with 33% starting on corticotropin
; 29% on topiramate; and fewer than 10% of patients on an oral or intravenous steroid, zonisamide, or vigabatrin (Sabril).
releasing factor: A key role inthe neurobiology ofaddiction.
is acquiring the New Drug Applications for purified corticotropin
gel and corticotropin-zinc hydroxide from Merck & Co.
Activation of brain corticotropin
releasing factor (CRF) receptors mediates stress-related inhibition of upper GI and stimulation of lower GI motor function through interaction with different CRF receptor subtypes.
Theoharides, "Acute immobilization stress triggers skin mast cell degranulation via corticotropin
releasing hormone, neurotensin, and substance P: a link to neurogenic skin disorders," Brain, Behavior, and Immunity, vol.
The Phase 2 trial, which involved 150 patients experiencing a major depressive episode, found no benefit for patients treated with the experimental drug, a corticotropin
releasing factor (CRF1) receptor antagonist called GSK561679.
A retrospective cohort study examined records of patients diagnosed with multiple sclerosis or retrobulbar neuritis who were treated with corticotropin
. (9) Corticotropin
has been reported to cause psychotic reactions in up to 11% of patients through a mechanism thought to mirror corticosteroid-induced psychosis (Box, page 68).
Hydrocortisone is widely used in patients with septic shock even though a survival benefit has been reported only in patients whose blood pressure remained low after fluid and vasopressor resuscitation and whose cortisol levels did not rise appropriately after they received corticotropin
Cushing's syndrome attributable to ectopic secretion of corticotropin
in a patient with two neuroendocrine tumors.
Central regulation of gastric emptying of solid nutrient meals by corticotropin
Acthar Gel (repository corticotropin
injection), an injectable drug indicated for the treatment of exacerbations associated with multiple sclerosis and Doral[R] (quazepam), that is indicated for the treatment of insomnia characterized by difficulty in falling asleep, frequent nocturnal awakenings, and/or early morning awakenings.
Their topics include the life cycle of depression, considerations of cognitive, psychodynamic, and cognitive-behavioral theories, the role of development and its implications in childhood and adolescent depression, developments in psychodynamic development psychopathology such as complex developmental pathways, and the integration of psychology and neurobiology in such treatment tools as corticotropin